ID G3Q233_GASAC Unreviewed; 216 AA.
AC G3Q233;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Nucleoside diphosphate kinase B {ECO:0000256|ARBA:ARBA00013499};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000023932.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000023932.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000023932.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Major role in the synthesis of nucleoside triphosphates other
CC than ATP. {ECO:0000256|ARBA:ARBA00003465}.
CC -!- SUBCELLULAR LOCATION: Cell projection, lamellipodium
CC {ECO:0000256|ARBA:ARBA00004510}. Cell projection, ruffle
CC {ECO:0000256|ARBA:ARBA00004466}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NDK family. {ECO:0000256|ARBA:ARBA00008142,
CC ECO:0000256|RuleBase:RU004011}.
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DR AlphaFoldDB; G3Q233; -.
DR STRING; 69293.ENSGACP00000023932; -.
DR Ensembl; ENSGACT00000023979.1; ENSGACP00000023932.1; ENSGACG00000018115.1.
DR eggNOG; KOG0888; Eukaryota.
DR GeneTree; ENSGT00940000159595; -.
DR InParanoid; G3Q233; -.
DR OMA; HNAISYW; -.
DR TreeFam; TF354225; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000018115; Expressed in testis and 3 other cell types or tissues.
DR GO; GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
DR GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
DR CDD; cd22970; DD_NDKH5-like; 1.
DR Gene3D; 1.20.890.10; cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain; 1.
DR Gene3D; 3.30.70.141; Nucleoside diphosphate kinase-like domain; 1.
DR InterPro; IPR007858; Dpy-30_motif.
DR InterPro; IPR034907; NDK-like_dom.
DR InterPro; IPR036850; NDK-like_dom_sf.
DR InterPro; IPR001564; Nucleoside_diP_kinase.
DR PANTHER; PTHR46161; NUCLEOSIDE DIPHOSPHATE KINASE; 1.
DR PANTHER; PTHR46161:SF1; NUCLEOSIDE DIPHOSPHATE KINASE HOMOLOG 5; 1.
DR Pfam; PF05186; Dpy-30; 1.
DR Pfam; PF00334; NDK; 1.
DR PRINTS; PR01243; NUCDPKINASE.
DR SMART; SM00562; NDK; 1.
DR SUPFAM; SSF54919; Nucleoside diphosphate kinase, NDK; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT DOMAIN 15..154
FT /note="Nucleoside diphosphate kinase-like"
FT /evidence="ECO:0000259|SMART:SM00562"
SQ SEQUENCE 216 AA; 24428 MW; 7DB9D3CDB5BC904D CRC64;
MQEEMNHTLY PRIYVEKTLS LIKPDAIHKA EEIEDIIRKS GFIILQQKQK LQLSPGQCCD
FYAHLYGMPL FPSLTAFMSS GPIIAMTLAR DNAIAHWKSI IGPVNSTEAR ETHPGCLRAK
YGSSELKNAL HGSASFHAAE REIKFMFPNS LIEPLPTREA NEVYLNRYVN PTLVRGLTEL
CKNKPLNPCM WLADWLTNND PNQPQTCDGA IVEEKE
//
