ID G3Q4I7_GASAC Unreviewed; 305 AA.
AC G3Q4I7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Bone morphogenetic protein 15 {ECO:0000313|Ensembl:ENSGACP00000024791.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000024791.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000024791.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000024791.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR AlphaFoldDB; G3Q4I7; -.
DR STRING; 69293.ENSGACP00000024791; -.
DR Ensembl; ENSGACT00000024840.1; ENSGACP00000024791.1; ENSGACG00000018750.1.
DR eggNOG; KOG3900; Eukaryota.
DR GeneTree; ENSGT00940000160940; -.
DR InParanoid; G3Q4I7; -.
DR OMA; CECKPAL; -.
DR TreeFam; TF316134; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000018750; Expressed in mesonephros.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR PANTHER; PTHR11848:SF22; BONE MORPHOGENETIC PROTEIN 15; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 181..305
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 305 AA; 34472 MW; 4F7012BA0AECC192 CRC64;
QNLQFMLSLY RSAAEPDGRP KQHRKFGSNT VRLLRPSAAS VRHLPASPDH RYSFTVQYNL
DTVPSEQLIR ASFIHLRSAP SSSSARPLRP PRCRAQIPSL GKASLVTLEP HERWTETDIT
AHVRRGRSRG PGGHLTLTAQ YWCTAWGGGF PSTGGSPTSR SRLFFYTWRR SGRTPPQRTP
RTRRLTCCED IHGANRRAAA PKNRCKLHSF RLSFDELGWG QYFIAPLVYN PRFCQGNCPR
VLTYGFHSPN HAIIQTVISD LGVGDVPPPS CVPYKYMPMS VLVVHKKKVE YRELEDMVAE
SCTCR
//
