ID   G3Q8V8_GASAC            Unreviewed;      1042 AA.
AC   G3Q8V8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=GRB10 interacting GYF protein 1a {ECO:0000313|Ensembl:ENSGACP00000026322.2};
GN   Name=GIGYF1 {ECO:0000313|Ensembl:ENSGACP00000026322.2};
OS   Gasterosteus aculeatus (Three-spined stickleback).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC   Gasterosteus.
OX   NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000026322.2, ECO:0000313|Proteomes:UP000007635};
RN   [1] {ECO:0000313|Ensembl:ENSGACP00000026322.2, ECO:0000313|Proteomes:UP000007635}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGACP00000026322.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GIGYF family.
CC       {ECO:0000256|ARBA:ARBA00038015}.
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DR   AlphaFoldDB; G3Q8V8; -.
DR   STRING; 69293.ENSGACP00000026322; -.
DR   Ensembl; ENSGACT00000026373.2; ENSGACP00000026322.2; ENSGACG00000019925.2.
DR   eggNOG; KOG1862; Eukaryota.
DR   GeneTree; ENSGT00940000159845; -.
DR   InParanoid; G3Q8V8; -.
DR   OMA; FHNTGEC; -.
DR   TreeFam; TF325513; -.
DR   Proteomes; UP000007635; Unassembled WGS sequence.
DR   Bgee; ENSGACG00000019925; Expressed in camera-type eye and 13 other cell types or tissues.
DR   CDD; cd00072; GYF; 1.
DR   Gene3D; 3.30.1490.40; -; 1.
DR   InterPro; IPR003169; GYF.
DR   InterPro; IPR035445; GYF-like_dom_sf.
DR   PANTHER; PTHR14445; GRB10 INTERACTING GYF PROTEIN; 1.
DR   PANTHER; PTHR14445:SF37; GRB10-INTERACTING GYF PROTEIN 1; 1.
DR   Pfam; PF02213; GYF; 1.
DR   SMART; SM00444; GYF; 1.
DR   SUPFAM; SSF55277; GYF domain; 1.
DR   PROSITE; PS50829; GYF; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007635}.
FT   DOMAIN          477..525
FT                   /note="GYF"
FT                   /evidence="ECO:0000259|PROSITE:PS50829"
FT   REGION          110..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          209..428
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          624..712
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          728..754
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          770..862
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        249..290
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        328..342
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        357..372
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        402..417
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        624..666
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        667..712
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        728..751
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        817..862
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1042 AA;  115391 MW;  53F517F231FF36C1 CRC64;
     MTAETLNFGP EWLRALSSGG SVTSPPPSPA MPKYKLAEYR YGREEMLALY IKDNKVPEDM
     QDKEFAAILQ DEPMQPLALV ALTEEEQRNF SMSVNSVAVL RLMGKGVGAP APAGVARGRG
     APRGGRGRGR GESGFYQRSI EEPEVGFGRS VREIHRSQSW DDRGERRFEK PLRREVGRPG
     FEEPVAPVVP GRKEYTRADS DNWRILREEQ EEEEGGGGSG GVAGVQFDTD GGACLLSDGG
     PRSAGWRDHT GPGESRRRKF DFDFRDSDGH GGSGGRRRAG SEGLEDDRDG LPEWCTDEED
     GEMGTFDSSG AFMTMKKGGK DSILEEEFEF KGIEEDEEEE CYADMDMKKS KEAGSAGGEG
     ETQQTSPSSS PPALIHCSPP ALEPRPSNAG PVVHMNLDAP ASSSLPPPPP SSAAPLHPPP
     GGDTEDDEGM KHLQQEAEKM VASLQDTSLE EECFTQTLQQ QESRNTAAAL PLSHEAAMKW
     FYKDPQGEIQ GPFTTVEMCE WFQAGYFTMT LLVKRGCDEG FQPLGDVIKM WGRVPFAPGP
     SPPPLLGNLD QDRLKKELAA AALYQQLQQQ QIFQLINRSE CGGVMYFWFP SFSTSTGILI
     ICPLRPVCSE QGMMPSMNRS MSVPDTGSMW DMHTSASQPS GGEASLWDIT MNPSTQGPTL
     EQLQKVGSVQ ERREAELRAK REEEEQRKRR EEKRRQQEDQ KRREEEDLFR RKQCRQQQEL
     IMKLLQQTPQ QQGPGASGSG WSGSPSSGLS KSGKPPALAL LEMQQEAERL LKQQQQQRAQ
     QRERVSRRDH SGLSMGSSSI GGQWADGVGM WGGGMEGKSS SGSSSGSMGM WDEAVKNQSG
     LRGNSNNNMG LKNSRSSPSL SEQYMMRRKR TEEEEKLLKL LQGMKPQDGF TTWCEQMLHA
     LNTSANNSSS SLDVATIVAY LKEVESPYAV LDFIRSYLGD TVEAKEFAKQ FLERRAKQKA
     NQQRQQQQVG LRDSMRGMNP STLQSMFQAN HMGKSGLYDI QGGKMKKKQP MMLHSDPSIL
     GYSFHNTGEC LSLNEMEMVE DY
//