ID G3QBW8_GASAC Unreviewed; 901 AA.
AC G3QBW8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=WD repeat-containing protein 44 {ECO:0000256|ARBA:ARBA00021207};
GN Name=WDR44 {ECO:0000313|Ensembl:ENSGACP00000027384.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000027384.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000027384.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000027384.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3QBW8; -.
DR STRING; 69293.ENSGACP00000027384; -.
DR Ensembl; ENSGACT00000027436.1; ENSGACP00000027384.1; ENSGACG00000020710.1.
DR eggNOG; KOG0283; Eukaryota.
DR GeneTree; ENSGT00940000157557; -.
DR InParanoid; G3QBW8; -.
DR OMA; SQECVRP; -.
DR TreeFam; TF329226; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000020710; Expressed in liver and 13 other cell types or tissues.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR040324; WDR44/Dgr2.
DR PANTHER; PTHR14221; WD REPEAT DOMAIN 44; 1.
DR PANTHER; PTHR14221:SF0; WD REPEAT-CONTAINING PROTEIN 44; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 498..529
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 594..627
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 634..668
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 548..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 849..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..247
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..566
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..583
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 901 AA; 98502 MW; 0DA1D48B692E36DE CRC64;
MASDTSDTEE FYDAPEDVNL TPSPKVSPTK SAVPFPQRSV NAAQDVSCGA SETPRDDPLL
IIDSIIEESQ KDCAGDVGEE VQLFDQLHDN AGAEPEPEEG SDAQEVPAEP AAPSVDPQLA
ERPRGQRESA ATDGAAACSP PACEPSAGSR EGVQPPDLTS TVGLAVLDGA VADHGVRGQR
PADILDQVPF AHRPPDSDSS SGPTKPPRQI TVEPDIVAST KKPPPSRPPP PGGGPPPRPP
PPFLPGLPSK KSQECLRPSG LEVSGDALEL SGLVSPSSTV RSLTKELQHS LDLASATSGE
KVVTAQENED GRSSSQSGEQ TPGPQRPRSD SGRELTDEEI LASVMIKNLD TGEEIPLIQA
EEKLPAAINP LTLHIMRRTK EYITNDAAQS DDDDKAQAPL ADTDGGKLKQ KTTQFKKFLG
KSVKKAKHLA EEYGEKAVNK VKSVRDEGRA EVFHTDQDDP SSSDDEGMPY TRPAKFKAAH
SFKGPFDFDQ IKVVQDLSGE HTGAVWTMKF SHCGRLLATA GQDNVVRIWV LKAAFDYFNN
MRMKYNTEGR VSPSPSQESL CSSKSDDHGA SCAPEDPDTE DRTAPFRQVP FCKYKGHTAD
LLDLSWSKNF FLLSSSMDKT VRLWHISRRE CLCCFQHIDF VTAIAFHPRD DRYFLSGSLD
GKLRLWNIPD KKVALWNEVD GQTRLITAAN FCQNGKYAVI GTYDGRCIFY DTERLKYHTQ
IHVRSTRGRN KVGRKITGIE PLPGENKILV TSNDSRIRLY DLRDLSLSMK YKGYVNSSSQ
IKASFSHDYS FIVSGSEDKY VYIWSTYHDL SKFTSVRRDR NDFWEGIKAH NAVVTSAIFA
PHPGLIVPQE AGADKPEAES KSLDSTDSET IPSGALKTDH TEVLLSADFT GAIKVFINVK
K
//
