ID G3QBX8_GASAC Unreviewed; 1045 AA.
AC G3QBX8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=RNA binding motif protein 27 {ECO:0000313|Ensembl:ENSGACP00000027394.1};
GN Name=RBM27 {ECO:0000313|Ensembl:ENSGACP00000027394.1};
OS Gasterosteus aculeatus (Three-spined stickleback).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Perciformes; Cottioidei; Gasterosteales; Gasterosteidae;
OC Gasterosteus.
OX NCBI_TaxID=69293 {ECO:0000313|Ensembl:ENSGACP00000027394.1, ECO:0000313|Proteomes:UP000007635};
RN [1] {ECO:0000313|Ensembl:ENSGACP00000027394.1, ECO:0000313|Proteomes:UP000007635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.;
RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGACP00000027394.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in the turnover of nuclear polyadenylated
CC (pA+) RNA. {ECO:0000256|ARBA:ARBA00043866}.
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DR AlphaFoldDB; G3QBX8; -.
DR STRING; 69293.ENSGACP00000027394; -.
DR Ensembl; ENSGACT00000027446.1; ENSGACP00000027394.1; ENSGACG00000020719.1.
DR eggNOG; KOG2135; Eukaryota.
DR GeneTree; ENSGT00510000046929; -.
DR InParanoid; G3QBX8; -.
DR OMA; CPMEHGL; -.
DR TreeFam; TF319253; -.
DR Proteomes; UP000007635; Unassembled WGS sequence.
DR Bgee; ENSGACG00000020719; Expressed in liver and 4 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR CDD; cd12517; RRM_RBM27; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 1.20.1390.10; PWI domain; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR002483; PWI_dom.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR045137; RBM26/27.
DR InterPro; IPR034451; RBM27_RRM.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR14398; RNA RECOGNITION RRM/RNP DOMAIN; 1.
DR PANTHER; PTHR14398:SF1; RNA-BINDING PROTEIN 27; 1.
DR Pfam; PF01480; PWI; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007635};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Zinc {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT DOMAIN 286..313
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 552..626
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT ZN_FING 286..313
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 115..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 513..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1001..1045
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 781..855
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 115..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..213
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..371
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 378..394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..417
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..663
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1045 AA; 115711 MW; 3C0AC48A8C633F8C CRC64;
MIIENVEALK SWLAKLLEPI CDADPSALAN YVVALVKKDK PEKDLKALCA DQLEVFLQKE
TTGFVDKLFE SLTTKNYLGN PAAKEVPKEE VKPPAVKAET VEKKMFFPLK AETLEEEREN
RRRRSPLRNR PDFNDARGRD DRRRDERKRR DFDRHGKSGG ESNRERERHE RRRGSPRGRS
YSRSLSRSRS GSRGKSRDTE HRGGRERKDT DCYNSSNKSG PPPLLPLPTP PHQFSSTSSA
GVSGAGGVPI VTPAHLPDST TDSWSGYYGT QRLDGAGKTF GSKSVSLKQR CRDYDEKGFC
VRGDLCPFDH GNDPLIVDDV NLPNMIPFPP PPVMPPTGLP RPPITEPPPP LRMPAMPPFG
QPPPPGVFPM SGPPLIATSG IDTPNHQTAI TSSPPIGPPG VGRPPPTLPP PPSPSSSVSL
RPQYVQSEYN YDPEGYNPES PGLTAAGRNP YRQFIPRVQT QRSNLIGLTS NEGQGSRDLL
AANIVIQTEP ATAASTPGNN VCRFNAEQDN RKRTIGPSTA EGPIVKKPWM EKPNFNNQHK
NTFPKRCYYV NTKLEVRKIP RDLNNIAKLN EHFSKFGTIV NIQVVFGGDP EAALIQYTKN
EEARRAISST EAVLNNRFIR VYWHREPGTN VTGLQEQSSG SQPAGSAASP ALLQQQQQHG
NMHKVSAKGP KPTDVRPLLM LMSLSRHAFA SLRSLSIYQQ GIKQHSPAAY VLNNIVPKHC
VPALPGLAAG TRLDGLNPNA DALTVVPALT NPQKSPYTST GLKSSSKSFG RTGKALEAQE
VLKKKQEAIK LQQDMRKKKQ EMLKTQMECQ KALINRLDKN RGMKPEERAN IMKTLKELTE
KIAQLQNEMN PASQVASVKP NHGQSKTKTD AQKELLDAEL DFHKKMSSGE DTTDLKRKLG
QLQVEATRLG LIRSPAGRGR GRGKMALEPG LVHVGRGRGR SREMMARCGS VNRMVVDHRP
RALAILGVTQ EEKEELMPHF VAANQGAKFK GRVLQISWYK PKTPSVATEP EEEEAKDDDT
TKDALLDVPT SDDEDDEYES RSWRR
//
