ID G3QF90_GORGO Unreviewed; 847 AA.
AC G3QF90;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=ATP binding cassette subfamily F member 1 {ECO:0000313|Ensembl:ENSGGOP00000000957.3};
GN Name=ABCF1 {ECO:0000313|Ensembl:ENSGGOP00000000957.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000000957.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000000957.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000000957.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000000957.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030044114; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030044115; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030044116; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3QF90; -.
DR Ensembl; ENSGGOT00000000978.3; ENSGGOP00000000957.3; ENSGGOG00000000968.3.
DR eggNOG; KOG0066; Eukaryota.
DR GeneTree; ENSGT00940000158329; -.
DR HOGENOM; CLU_000604_36_5_1; -.
DR TreeFam; TF105207; -.
DR Proteomes; UP000001519; Chromosome 6.
DR Bgee; ENSGGOG00000000968; Expressed in testis and 5 other cell types or tissues.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03221; ABCF_EF-3; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19211:SF14; ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3; 1.
DR PANTHER; PTHR19211; ATP-BINDING TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT DOMAIN 306..550
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 627..842
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..63
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 847 AA; 96224 MW; F2A27302BCB11A5C CRC64;
MPKAPKQQPP EPEWIGDGES TSPSDKVVKK GKKDKKIKKT FFEELAVEDK QAGEEEKVLK
EKEQQQQQQQ QQQQQQKKKR DTRKGRRKKD VDDDGEEKEL MERLKKLSVP ASDEEDEVPA
PKPRGGKKTK GGNVFAALIQ DQSEEEEEEE KHPPKPAKPE KNRINKAVSE EQQPALKGKK
GKEEKSKGKA KPQNKFAALD NEEEDKEEEI IKEKEPPKQG KEKAKKAEQG SEEEGEGEEE
EEEGESKADD PYAHLSKKEK KKLKKQMEYE RQVASLKAAN AAENDFSVSQ AEMSSRQAML
ENASDIKLEK FSISAHGKEL FVNADLYIVA GRRYGLVGPN GKGKTTLLKH IANRALSIPP
NIDVLLCEQE VVADETPAVQ AVLRADTKRL KLLEEERRLQ GQLEQGDDTA AERLEKVYEE
LRATGAAAAE AKARRILAGL GFDPEMQNRP TQKFSGGWRM RVSLARALFM EPTLLMLDEP
TNHLDLNAVI WLNNYLQGWR KTLLIVSHDQ GFLDDVCTDI IHLDAQRLHY YRGNYMTFKK
MYQQKQKELL KQYEKQEKKL KELKAGGKST KQAEKQTKEA LTRKQQKCRR KNQDEESQEA
PELLKRPKEY TVRFTFPDPP PLSPPVLGLH GVTFGYEGQK PLFKNLDFGI DMDSRICIVG
PNGVGKSTLL LLLTGKLTPT HGEMRKNHRL KIGFFNQQYA EQLRMEETPT EYLQRGFNLP
YQDARKCLGR FGLESHAHTI QICKLSGGQK ARVVFAELAC REPDVLILDE PTNNLDIESI
DALGEAINEY KGAVIVVSHD ARLITETNCQ LWVVEEQSVS QIDGDFEDYK REVLEALGEV
MVSRPRE
//
