ID G3QUY8_GORGO Unreviewed; 1104 AA.
AC G3QUY8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=BTB domain containing 11 {ECO:0000313|Ensembl:ENSGGOP00000006549.2};
GN Name=ABTB3 {ECO:0000313|Ensembl:ENSGGOP00000006549.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000006549.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000006549.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000006549.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000006549.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030086533; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030086534; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030086535; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030086536; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030086537; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030086538; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030086539; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030086540; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030086541; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030086542; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004053870.1; XM_004053822.2.
DR AlphaFoldDB; G3QUY8; -.
DR STRING; 9593.ENSGGOP00000006549; -.
DR Ensembl; ENSGGOT00000006721.3; ENSGGOP00000006549.2; ENSGGOG00000006683.3.
DR GeneID; 101148139; -.
DR KEGG; ggo:101148139; -.
DR CTD; 121551; -.
DR eggNOG; ENOG502QSQY; Eukaryota.
DR GeneTree; ENSGT00940000156419; -.
DR HOGENOM; CLU_001918_0_0_1; -.
DR InParanoid; G3QUY8; -.
DR OMA; ASMSDGH; -.
DR OrthoDB; 1085234at2759; -.
DR TreeFam; TF106437; -.
DR Proteomes; UP000001519; Chromosome 12.
DR Bgee; ENSGGOG00000006683; Expressed in frontal cortex and 5 other cell types or tissues.
DR GO; GO:0098978; C:glutamatergic synapse; IEA:Ensembl.
DR GO; GO:0030165; F:PDZ domain binding; IEA:Ensembl.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0035640; P:exploration behavior; IEA:Ensembl.
DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR GO; GO:0060395; P:SMAD protein signal transduction; IBA:GO_Central.
DR GO; GO:0035249; P:synaptic transmission, glutamatergic; IEA:Ensembl.
DR CDD; cd18527; BACK_BTBD11; 1.
DR CDD; cd18351; BTB_POZ_BTBD11; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR047824; BTBD11_BACK.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR46071; ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR46071:SF1; ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN BTBD11; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00248; ANK; 4.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47113; Histone-fold; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519}.
FT REPEAT 603..635
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 649..681
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 687..713
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 923..983
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 260..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1104 AA; 120912 MW; 5F2D084749A2E574 CRC64;
MARRGKKPVV RTLEDLTLDS GYGGAADSVR SSNLSLCCSD SHPASPYGGS CWPPLADSMH
SRHNSFDTVN TALVEDSEGL DCAGQHCSRL LPDLDEVPWT LQELEALLLR SRDPRAGPAV
PGGLPKDALA KLSTLVSRAL VRIAKEAQRL SLRFAKCTKY EIQSAMEIVL SWGLAAHCTA
AALAALSLYN MSSAGGDRLG RGKSARCGLT FSVGRVYRWM VDSRVALRIH EHAAIYLTAC
MESLFRDIYS RVVASGVPRS CSGPGSGSGS GPGPSSGPGA APAADKEREA PGGGVASGGA
CSAASSASGG SSCCAPPAAA AAAVPPAAAA NHHHHHHHAL HEAPKFTVET LEHTVNNDSE
IWGLLQPYQH LICGKNASGV LCLPDSLNLH RDPQRSNKPG ELPMFSQSEL RTIEQSLLAT
RVGSIAELSD LVSRAMHHLQ PLNAKHHGNG TPLHHKQGAL YWEPEALYTL CYFMHCPQME
WENPNVEPSK VNLQVERPFL VLPPLMEWIR VAVAHAGHRR SFSMDSDDVR QAARLLLPGV
DCEPRQLRAD DCFCASRKLD AVAIEAKFKQ DLGFRMLNCG RTDLVKQAVS LLGPDGINTM
SEQGMTPLMY ACVRGDEAMV QMLLDAGADL NVEVVSTPHK YPSVHPETRH WTALTFAVLH
GHIPVVQLLL DAGAKVEGSV EHGEENYSET PLQLAAAVGN FELVSLLLER GADPLIGTMY
RNGISTTPQG DMNSFSQAAA HGHRNVFRKL LAQPEKEKSD ILSLEEILAE GTDLAETAPP
PLCASRNSKA KLRALREAMY HSAEHGYVDV TIDIRSIGVP WTLHTWLESL RIAFQQHRRP
LIQCLLKEFK TIQEEEYTEE LVTQGLPLMF EILKASKNEV ISQQLCVIFT HCYGPYPIPK
LTEIKRKQTS RLDPHFLNNK EMSDVTFLVE GRPFYAHKVL LFTASPRFKA LLSSKPTNDG
TCIEIGYVKY SIFQLVMQYL YYGGPESLLI KNNEIMELLS AAKFFQLEAL QRHCEIICAK
SINTDNCVDI YNHAKFLGVT ELSAYCEGYF LKNMMVLIEN EAFKQLLYDK NGEGTGQDVL
QDLQRTLAIR IQSIHLSSSK GSVV
//
