ID G3QYI2_GORGO Unreviewed; 505 AA.
AC G3QYI2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=PHD finger protein 21B {ECO:0000313|Ensembl:ENSGGOP00000007918.3};
GN Name=PHF21B {ECO:0000313|Ensembl:ENSGGOP00000007918.3};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000007918.3, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000007918.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000007918.3, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000007918.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030121532; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030121533; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030121534; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030121535; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030121536; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CABD030121537; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3QYI2; -.
DR STRING; 9593.ENSGGOP00000007918; -.
DR Ensembl; ENSGGOT00000008134.3; ENSGGOP00000007918.3; ENSGGOG00000008097.3.
DR eggNOG; KOG0383; Eukaryota.
DR GeneTree; ENSGT00940000161105; -.
DR HOGENOM; CLU_020260_1_0_1; -.
DR InParanoid; G3QYI2; -.
DR OMA; VCMDQRD; -.
DR TreeFam; TF331518; -.
DR Proteomes; UP000001519; Chromosome 22.
DR Bgee; ENSGGOG00000008097; Expressed in testis and 4 other cell types or tissues.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15524; PHD_PHF21B; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24102; PHD FINGER PROTEIN; 1.
DR PANTHER; PTHR24102:SF18; PHD FINGER PROTEIN 21B; 1.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00249; PHD; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 326..373
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 59..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 212..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 397..424
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 80..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..196
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 54490 MW; 497DF86E3468F3FF CRC64;
NGDLKKQLHE RQPRIAALSD KQALGTITAV PVTGPQVSSL QRLAGQGAAV LPQVRPKTLI
PDSLPVAPGR DRPPKQPPTF QKATVVSVKN PSPALPTANN TVSHVPAPGS QPQALAEPAA
LASPLSSAGV AYAIISTSPS NAAAMAPSTA VSVVSDSIKV QPLLISADNK PPPPLLSSPH
PATHHCPTPP SPSLSPSPLH GIFQVIIIQP QVQTQPESTA ESRPPTEEPS QGAQATKKKK
EDRPPTQENP EKIAFMVALG LVTTEHLEEI QSKRQERKRR STANPAYSGL LETERKRLAS
NYLNNPLFLT ARANEDPCWK NEITHDEHCA ACKRGANLQP CGTCPGAYHL SCLEPPLKTA
PKGVWVCPRC QQKALKKDEG VPWTGMLAIV HSYVTHKTVK EEEKQKLLQR GSELQNEHQQ
LEERDRRLAS AVQKCLELKT SLLARQRGTQ SSLDRLRALL RLIQGEQLLQ VTMTTTSPAP
LLAGPWTKPS VAATHPTVQH PQGHN
//
