GenomeNet

Database: UniProt
Entry: G3R1B9_GORGO
LinkDB: G3R1B9_GORGO
Original site: G3R1B9_GORGO 
ID   G3R1B9_GORGO            Unreviewed;      4793 AA.
AC   G3R1B9;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   30-AUG-2017, entry version 42.
DE   SubName: Full=Ryanodine receptor 3 {ECO:0000313|Ensembl:ENSGGOP00000008975};
GN   Name=RYR3 {ECO:0000313|Ensembl:ENSGGOP00000008975};
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Gorilla.
OX   NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000008975, ECO:0000313|Proteomes:UP000001519};
RN   [1] {ECO:0000313|Ensembl:ENSGGOP00000008975, ECO:0000313|Proteomes:UP000001519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Scally A.;
RT   "Insights into the evolution of the great apes provided by the gorilla
RT   genome.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGGOP00000008975}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSGGOP00000008975}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   STRING; 9593.ENSGGOP00000008975; -.
DR   Ensembl; ENSGGOT00000009224; ENSGGOP00000008975; ENSGGOG00000009119.
DR   GeneTree; ENSGT00760000119152; -.
DR   InParanoid; G3R1B9; -.
DR   OMA; HDECLTI; -.
DR   OrthoDB; EOG091G00T0; -.
DR   TreeFam; TF315244; -.
DR   Proteomes; UP000001519; Chromosome 15.
DR   Bgee; ENSGGOG00000009119; -.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 3.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001519};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4106   4130       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4334   4354       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4402   4421       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4533   4551       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4594   4615       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4674   4697       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       19     74       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN       81    126       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      134    188       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      194    252       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      262    319       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      504    715       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN      931   1127       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1173   1385       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     3842   3877       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   COILED     4256   4283       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   4793 AA;  543694 MW;  147075E1EB51C8A7 CRC64;
     MLANTGENGG EGAAQGGGHR TLLYGHAVLL RHSFSGMYLT CLTTSRSQTD KLAFDVGLRE
     HATGEACWWT IHPASKQRSE GEKVRIGDDL ILVSVSSERY LHLSVSNGNI QVDASFMQTL
     WNVHPTCSGS SIEEGYLLGG HVVRLFHGHD ECLTIPSTDQ NDSQHRRIFY EAGGAGTRAR
     SLWRVEPLRI SWSGSNIRWG QAFRLRHLTT GHYLALTEDQ GLILQDRAKS DTKSTAFSFR
     ASKELKEKLD SSHKRDIEGM GVPEIKYGDS VCFVQHIASG LWVTYKAQDA KTSRLGPLKR
     KVILHQEGHM DDGLTLQRCQ REESQAARII RNTTALFSQF VSGNNRTAAP ITLPIEEVLQ
     TLQDLIAYFQ PPEEEMRHED KQNKLRSLKN RQNLFKEEGM LALVLNCIDR LNIYNSVAHF
     AGIVREESGM AWKEILNLLY KLLAALIRGN RNNCAQFSNN LDWLISKLDR LESSSGILEV
     LHCILTESPE ALNLIAEGHI KSIISLLDKH GRNHKVLDIL CSLCLCNGVA VRANQNLICD
     NLLPRRNLLL QTRLINDVTS IRPNIFLGVA EGSAQYKKWY FELIIDQVDP FLTAEPTHLR
     VGWASSSGYA PYPGGGEGWG GNGVGDDLYS YGFDGLHLWS GRIPRAVASI NQHLLRSDDV
     VSCCLDLGVP SISFRINGQP VQGMFENFNT DGLFFPVMSF SAGVKVRFLM GGRHGEFKFL
     PPSGYAPCYE ALLPKEKMRL EPVKEYKRDA DGIRDLLGTT QFLSQASFIP CPVDTSQVVL
     PPHLEKIRDR LAENIHELWG MNKIELGWTF GKIRDDNKRQ HPCLVEFSKL PETEKNYNLQ
     MSTETLKTLL ALGCHIAHVN PAAEEDLKKV KLPKNYMMSN GYKPAPLDLS DVKLLPPQEI
     LVDKLAENAH NVWAKDRIKQ GWTYGIQQDL KNKRNPRLVP YALLDERTKK SNRDSLREAV
     RTFVGYGYNI EPSDQELADS AVEKVSIDKI RFFRVERSYA VRSGKWYFEF EVVTGGDMRV
     GWARPGCRPD VELGADDQAF VFEGNRGQRW HQGSGYFGRT WQPGDVVGCM INLDDASMIF
     TLNGELLITN KGSELAFADY EIENGFVPIC CLGLSQIGRM NLGTDASTFK FYTMCGLQEG
     FEPFAVNMNR DVAMWFSKRL PTFVNVPKDH PHIEVMRIDG TMDSPPCLKV THKTFGTQNS
     NADMIYCRLS MPVECHSSFS HSPCLDSEAF QKRKQMQEIL SHTTTQCYYA IRIFAGQDPS
     CVWVGWVTPD YHLYSEKFDL NKNCTVTVTL GDERGRVHES VKRSNCYMVW GGDIVASSQR
     SNRSNVDLEI GCLVDLAMGM LSFSANGKEL GTCYQVEPNT KVFPAVFLQP TSTSLFQFEL
     GKLKNAMPLS AAIFKSEEKN PVPQCPPRLD VQTIQPVLWS RMPNSFLKVE TERVSERHGW
     VVQCLEPLQM MALHIPEENR CVDILELCEQ EDLMRFHYHT LRLYSAVCAL GNSRVAYALC
     SHVDLSQLFY AIDNKYLPGL LRSGFYDLLI SIHLANAKER KLMMKNEYII PITSTTRNIR
     LFPDESKRHG LPGVGLRTCL KPGFRFSTPC FVVTGEDHQK QSPEIPLESL RTKALSMLTE
     AVQCSGAHIR DPVGGSVEFQ FVPVLKLIGT LLVMGVFDDD DVRQILLLID PSVFGEHSAG
     TEEGAEKEEV TQVEEKAVEA GEKAGKEAPV KGLLQTRLPE SVKLQMCELL SYLCDCELQH
     RVEAIVAFGD IYVSKLQANQ KFRYNELMQA LNMSAALTAR KTKEFRSPPQ EQINMLLNFQ
     LGENCPCPEE IREELYDFHE DLLLHCGKLP RERLCPRRTS WTGKLCALVY KIKGPPKPEK
     EQPTEEEERC PTTLKELISQ TMICWAQEDQ IQDSELVRMM FNLLRRQYDS IGELLQALRK
     TYTISHTSVS DTINLLAALG QIRSLLSVRM GKEEELLMIN GLGDIMNNKV FYQHPNLMRV
     LGMHETVMEV MVNVLGTEKS QIAFPKMVAS CCRFLCYFCR ISRQNQKAMF EHLSYLLENS
     SVGLASPSMR GSTPLDVAAS SVMDNNELAL SLEEPDLEKV VTYLAGCGLQ SCPMLLAKGY
     PDVGWNPIEG ERYLSFLRFA VFVNSESVEE NASVVVKLLI RRPECFGPAL RGEGGNGLLA
     AMQGAIKISE NPALDLPSQG YKREVSTEDD EEEEEIVHMG NAIMSFYSAL IDLLGRCAPE
     MHLIQTGKGE AIRIRSILRS LVPTEDLVGI ISIPLKLPSL NKDGSVSEPD MAANFCPDHK
     APMVLFLDRV YGIKDQTFLL HLLEVGFLPD LRASASLDTV SLSTTEAALA LNRYICSAVL
     PLLTRCAPLF AGTEHCTSLI DSTLQTIYRL SKGRSLTKAQ RDTIEECLLA ICNHLRPSML
     QQLLRRLVFD VPQLNEYCKM PLKLLTNHYE QCWKYYCLPS GWGSYGLAVE EELHLTEKLF
     WGIFDSLSHK KYDPDLFRMA LPCLSAIAGA LPPDYLDTRI TATLEKQISV DADGNFDPKP
     INTMNFSLPE KLEYVVTKYA EHSHDKWACD KSQSGWKYGI SLDENVKTHP LIRPFKTLTE
     KEKEIYRWPA RESLKTMLAV GWTVERTKEG EALVQQRENE KLRSVSQANQ GNSYSPAPLD
     LSNVVLSREL QGMVEVVAEN YHNIWAKKKK LELESKGGGS HPLLVPYDTL TAKEKFKDRE
     KAQDLFKFLQ VNGVIVSRGM KDMELDASSM EKRFAYKFLK KILKYVDSAQ EFIAHLEAIV
     SSGKTEKSPH DQEIKFFAKV LLPLVDQYFT NHCLYFLSSP LKPLSSSGYA SHKEKEMVAS
     LFCKLAALVR HRISLFGSDS TTMVSCLHIL AQTLDTRTVM KSGSELVKAG LRAFFENAAE
     DLEKTSENLK LGKFTHSRTQ IKGVSQNINY TTVALLPILT SIFEHVTQHQ FGMDLLLGDV
     QISCYHILCS LYSLGTGKNI YVERQRPALG ECLASLAAAI PVAFLEPTLN RYNPLSVFNT
     KTPRERSILG MPDTVEDMCP DIPQLEGLMK EINDLAESGA RYTEMPHVIE VILPMLCNYL
     SYWWERGPEN LPPSTGPCCT KVTSEHLSLI LGNILKIINN NLGIDEASWM KRIADAVYAQ
     PIISKARPDL LRSHFIPTLE KLKKKAVKTV QEEEQLKADG KGDTQEAELL ILDEFAVLCR
     DLYAFYPMLI RYVDNNRPRS NWLKSPDADS DQLFRMVAEV FILWCKSHNF KREEQNFVIQ
     NEINNLAFLT GDSKSKMSKA MQVKSGGQDQ ERKKTKRRGD LYSIQTSLIV AALKKMLPIG
     LNMCTPGDQE LISLAKSRYS HRDTDEEVRE HLRNNLHLQE KSDDPAVKWQ LNLYKDVLKS
     EEPFNPEKTV ERVQRISAAV FHLEQVEQPL RSKKAVWHKL LSKQRKRAVV ACFRMAPLYN
     LPRHRSINLF LHGYQRFWIE TEEYSFEEKL VQDLAKSPKV EEEEEEETEK QPDPLHQIIL
     YFSRNALTER SKLEDDPLYT SYSSMMAKSC QSGEDEEEDE DKEKTFEEKE MEKQKTLYQQ
     ARLHERGAAE MVLQMISASK GEMSPMVVET LKLGIAILNG GNAGVQQKML DYLKEKKDAG
     FFQSLSGLMQ SCRSVLDLNA FERQNKAEGL GMVTEEGTLI VRERGEKVLQ NDEFTRDLFR
     FLQLLCEGHN SDFQNFLRTQ MGNTTTVNVI ISTVDYLLRL QESISDFYWY YSGKDIIDES
     GQHNFSKALA VTKQIFNSLT EYIQGPCIGN QQSLAHSRLW DAVVGFLHVF ANMQMKLSQD
     SSQIELLKEL LDLLQDMVVM LLSLLEGNVV NGTIGKQMVD TLVESSTNVE MILKFFDMFL
     KLKDLTSSDT FKEYDPDGKG IISKKEFQKA MEGQKQYTQS EIDFLLSCAE ADENDMFNYI
     DFVDRFHEPA KDIGFNVAVL LTNLSEHMPN DSRLKCLLDP AESVLNYFEP YLGRIEIMGG
     AKKIERVYFE ISESSRTQWE KPQVKESKRQ FIFDVVNEGG EQEKMELFVN FCEDTIFEMQ
     LASQISESDS ADRPEEEEED EDSSYVLEIA GEEEEDGSLE PASAFAMACA SVKRNVTDFL
     KRATLKNLRK QYRNVKKMTA KELVKVLFSF FWMLFVGLFQ LLFTILGGIF QILWSTVFGG
     GLVEGAKNIR VTKILGDMPD PTQFGIHDDT MEAERAEVME PGITTELVHF IKGEKGDTDI
     MSDLFGLHPK KEGSLKHGPE VGLGDLSEII GKNEPPTLQS TVQKKRKAQA AEMKAANEAE
     GKVESEKADM EDGEKEDKDK EEEQAEYLWT EVTKKKKRRC GQKVEKPEAF TANFFKGLEI
     YQTKLLHYLA RNFYNLRFLA LFVAFAINFI LLFYKVTEEP LEEETEDVAN LWNSFNDEEE
     EEAMVFFVLQ ESTGYMAPTL RALAIIHTII SLVCVVGYYC LKVPLVVFKR EKEIARKLEF
     DGLYITEQPS EDDIKGQWDR LVINTPSFPN NYWDKFVKRK VINKYGDLYG AERIAELLGL
     DKNALDFSPV EETKAEAASL VSWLSSIDMK YHIWKLGVVF TDNSFLYLAW YTTMSVLGHY
     NNFFFAAHLL DIAMGFKTLR TILSSVTHNG KQLVLTVGLL AVVVYLYTVV AFNFFRKFYN
     KSEDDDEPDM KCDDMMTCYL FHMYVGVRAG GGIGDEIEDP AGDPYEMYRI VFDITFFFFV
     IVILLAIIQG LIIDAFGELR DQQEQVREDM ETKCFICGIG NDYFDTTPHG FETHTLQEHN
     LANYLFFLMY LINKDETEHT GQESYVWKMY QERCWDFFPA GDCFRKQYED QLG
//
DBGET integrated database retrieval system