GenomeNet

Database: UniProt
Entry: G3R4X7_GORGO
LinkDB: G3R4X7_GORGO
Original site: G3R4X7_GORGO 
ID   G3R4X7_GORGO            Unreviewed;       737 AA.
AC   G3R4X7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   25-OCT-2017, entry version 42.
DE   SubName: Full=Two pore segment channel 2 {ECO:0000313|Ensembl:ENSGGOP00000010343};
GN   Name=TPCN2 {ECO:0000313|Ensembl:ENSGGOP00000010343};
OS   Gorilla gorilla gorilla (Western lowland gorilla).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Gorilla.
OX   NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000010343, ECO:0000313|Proteomes:UP000001519};
RN   [1] {ECO:0000313|Ensembl:ENSGGOP00000010343, ECO:0000313|Proteomes:UP000001519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Scally A.;
RT   "Insights into the evolution of the great apes provided by the gorilla
RT   genome.";
RL   Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSGGOP00000010343}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSGGOP00000010343}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   Ensembl; ENSGGOT00000010647; ENSGGOP00000010343; ENSGGOG00000010594.
DR   GeneTree; ENSGT00530000063660; -.
DR   Proteomes; UP000001519; Chromosome 11.
DR   Bgee; ENSGGOG00000010594; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005765; C:lysosomal membrane; IEA:InterPro.
DR   GO; GO:0072345; F:NAADP-sensitive calcium-release channel activity; IEA:InterPro.
DR   GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028798; TPC2.
DR   PANTHER; PTHR10037:SF92; PTHR10037:SF92; 1.
DR   Pfam; PF00520; Ion_trans; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001519};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     64     82       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    139    162       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    202    222       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    270    295       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    419    438       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    450    474       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    486    508       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    566    586       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    624    647       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    659    679       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       74    298       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      414    682       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   737 AA;  83954 MW;  63EE61B2959ACBE5 CRC64;
     QQPRVPSMLG ERGRGLLCSC AAARWDLCID QAVVFIEDAI QYRSINHRVD ASSMWLYRRY
     YSNVCQRTLS FTIFLILFLA FIETPSSLTS TADVRYRAAP WEPPCGLTES VEVLCLLVFA
     ADLSVKGYLF GWAHFQKNLW LLGYLVVLVV SLVDWTVSLS LVCHEPLRIR RLLRPFFLLQ
     NSSMMKKTLK CIRWSLPEMA SVGLLLAIHL CLFTMFGMLL FAGGKQDDGQ DRERLTYFQN
     LPESLTSLLV LLTTANNPDV MIPAYSKNRA YAIFFIVFTV IGSLFLMNLL TAIIYSQFRG
     YLMKSLQTSL FRRRLGTRAA FEVLSSMVGE GGAFPQAVGV KPQNLLQVLR KVQLDSSHKQ
     AMMEKVRSYG SVLLSAEEFQ KLFNELDRSV VKEHPPRPGY QSPFLQSAQF LFGHYYFDYL
     GNLIALANLV TICVFLVLDA DVLPAERDDF ILGILNCVFI VYYLLEMLLK VFALGLRGYL
     SYPSNVFDGL LTIVLLLKVL EISTLAVYRL PHPGWRPEML GLLSLWDMTR MLNMLIVFRF
     LRIIPSMKPM AVVASTVLGL VQNMRAFGGI LVVVYYVFAI IGINLFRGVI VAPPGNSSLA
     PANGSAPCGS FEQLEYWANN FDDFAAALVT LWNLMVVNNW QVFLDAYRRY SGPWSKIYFV
     LWWLVSSVIW VNLFLALILE NFLHKWDPRS HLQPLAGTPE ATYQMTVELL FRDILEEPGE
     DELTERLSQH PHLWLCR
//
DBGET integrated database retrieval system