ID G3RRY6_GORGO Unreviewed; 331 AA.
AC G3RRY6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 2.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Heterogeneous nuclear ribonucleoprotein H3 {ECO:0000313|Ensembl:ENSGGOP00000018561.2};
GN Name=HNRNPH3 {ECO:0000313|Ensembl:ENSGGOP00000018561.2};
OS Gorilla gorilla gorilla (Western lowland gorilla).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Gorilla.
OX NCBI_TaxID=9595 {ECO:0000313|Ensembl:ENSGGOP00000018561.2, ECO:0000313|Proteomes:UP000001519};
RN [1] {ECO:0000313|Ensembl:ENSGGOP00000018561.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Scally A.;
RT "Insights into the evolution of the great apes provided by the gorilla
RT genome.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSGGOP00000018561.2, ECO:0000313|Proteomes:UP000001519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=22398555; DOI=10.1038/nature10842;
RA Scally A., Dutheil J.Y., Hillier L.W., Jordan G.E., Goodhead I.,
RA Herrero J., Hobolth A., Lappalainen T., Mailund T., Marques-Bonet T.,
RA McCarthy S., Montgomery S.H., Schwalie P.C., Tang Y.A., Ward M.C., Xue Y.,
RA Yngvadottir B., Alkan C., Andersen L.N., Ayub Q., Ball E.V., Beal K.,
RA Bradley B.J., Chen Y., Clee C.M., Fitzgerald S., Graves T.A., Gu Y.,
RA Heath P., Heger A., Karakoc E., Kolb-Kokocinski A., Laird G.K., Lunter G.,
RA Meader S., Mort M., Mullikin J.C., Munch K., O'Connor T.D., Phillips A.D.,
RA Prado-Martinez J., Rogers A.S., Sajjadian S., Schmidt D., Shaw K.,
RA Simpson J.T., Stenson P.D., Turner D.J., Vigilant L., Vilella A.J.,
RA Whitener W., Zhu B., Cooper D.N., de Jong P., Dermitzakis E.T.,
RA Eichler E.E., Flicek P., Goldman N., Mundy N.I., Ning Z., Odom D.T.,
RA Ponting C.P., Quail M.A., Ryder O.A., Searle S.M., Warren W.C.,
RA Wilson R.K., Schierup M.H., Rogers J., Tyler-Smith C., Durbin R.;
RT "Insights into hominid evolution from the gorilla genome sequence.";
RL Nature 483:169-175(2012).
RN [3] {ECO:0000313|Ensembl:ENSGGOP00000018561.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CABD030070232; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004049546.1; XM_004049498.2.
DR RefSeq; XP_018890336.1; XM_019034791.1.
DR RefSeq; XP_018890337.1; XM_019034792.1.
DR STRING; 9593.ENSGGOP00000050824; -.
DR Ensembl; ENSGGOT00000023812.2; ENSGGOP00000018561.2; ENSGGOG00000025378.2.
DR Ensembl; ENSGGOT00000045292.1; ENSGGOP00000050824.1; ENSGGOG00000025378.2.
DR GeneID; 101152200; -.
DR CTD; 3189; -.
DR eggNOG; KOG4211; Eukaryota.
DR GeneTree; ENSGT00940000157720; -.
DR HOGENOM; CLU_032003_1_0_1; -.
DR OMA; WAGKHNG; -.
DR OrthoDB; 314723at2759; -.
DR TreeFam; TF316157; -.
DR Proteomes; UP000001519; Chromosome 10.
DR Bgee; ENSGGOG00000025378; Expressed in cerebellum and 6 other cell types or tissues.
DR GO; GO:0005654; C:nucleoplasm; IBA:GO_Central.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0030855; P:epithelial cell differentiation; IEA:Ensembl.
DR GO; GO:0043484; P:regulation of RNA splicing; IBA:GO_Central.
DR CDD; cd12732; RRM2_hnRNPH3; 1.
DR CDD; cd12735; RRM3_hnRNPH3; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR034970; hnRNPH3_RRM2.
DR InterPro; IPR034969; hnRNPH3_RRM3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR13976:SF36; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN H3; 1.
DR PANTHER; PTHR13976; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED; 1.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001519};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 16..93
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 180..255
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 331 AA; 35239 MW; A3BA8D0F5FC07369 CRC64;
MDWVMKHNGP NDASDGTVRL RGLPFGCSKE EIVQFFQGLE IVPNGITLTM DYQGRSTGEA
FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY DPPRRLLGQR PGPYDRPIGG
RGGYYGAGRG SYGGFDDYGG YNNYGYGNDG FDDRMRDGRG MGGHGYGGAG DASSGFHGGH
FVHMRGLPFR ATENDIANFF SPLNPIRVHI DIGADGRATG EADVEFVTHE DAVAAMSKDK
NNMQHRYIEL FLNSTPGGGS GMGGSGMGGY GRDGMDNQGG YGSVGRMGMG NNYSGGYGTP
DGLGGYGRGG GGSGGYYGQG GMSGGGWRGM Y
//
