ID G3SPR7_LOXAF Unreviewed; 618 AA.
AC G3SPR7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Nuclear cap-binding protein subunit 3 {ECO:0000256|ARBA:ARBA00019876};
GN Name=NCBP3 {ECO:0000313|Ensembl:ENSLAFP00000001728.4};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000001728.4, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000001728.4, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000001728.4,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000001728.4}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000001728.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NCBP3 family.
CC {ECO:0000256|ARBA:ARBA00006069}.
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DR RefSeq; XP_003416893.1; XM_003416845.2.
DR AlphaFoldDB; G3SPR7; -.
DR STRING; 9785.ENSLAFP00000001728; -.
DR Ensembl; ENSLAFT00000002067.4; ENSLAFP00000001728.4; ENSLAFG00000002067.4.
DR GeneID; 100671489; -.
DR KEGG; lav:100671489; -.
DR CTD; 55421; -.
DR eggNOG; ENOG502QRX4; Eukaryota.
DR GeneTree; ENSGT00390000005712; -.
DR HOGENOM; CLU_488838_0_0_1; -.
DR InParanoid; G3SPR7; -.
DR OMA; QYSRPRP; -.
DR OrthoDB; 37636at2759; -.
DR TreeFam; TF331339; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005845; C:mRNA cap binding complex; IEA:Ensembl.
DR GO; GO:0005846; C:nuclear cap binding complex; IEA:Ensembl.
DR GO; GO:0016607; C:nuclear speck; IEA:Ensembl.
DR GO; GO:0003729; F:mRNA binding; IEA:Ensembl.
DR GO; GO:0000340; F:RNA 7-methylguanosine cap binding; IEA:Ensembl.
DR GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
DR GO; GO:0006406; P:mRNA export from nucleus; IEA:Ensembl.
DR GO; GO:0006408; P:snRNA export from nucleus; IEA:Ensembl.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR019416; NCBP3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR PANTHER; PTHR16291; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3; 1.
DR PANTHER; PTHR16291:SF0; NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3; 1.
DR Pfam; PF10309; NCBP3; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT REGION 15..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 470..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..233
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 340..361
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..594
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..611
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 618 AA; 70393 MW; DDFA181096DCED14 CRC64;
MAAVRGLRVS VKAEAPAGPA LGLPSPEAEP GLERGEPEPM EVEEGELEIV PVRRSLKELI
PDTSRRYENK AGSFITGIDV TSKEAIEKKE QRAKRFHFRS EVNLAQRNVA LDRDMMKKAI
PKVRLETIYI CGVDEMSTQD IFSYFKEYPP AHIEWLDDTS CNVVWLDEMT ATRALINMSS
LPALDKIRSR DANEDKSSEK SKKDKQEDSS DDDEAEEGEV EDENSSDVEL DTLSQVEEES
LLRNDLRPAN KLAKGNRLFM RFATKDDKKE LGAARRSQYY MKYGNPNYGG MKGILSNSWK
RRYHSRRIQR DVIKKRALIG DDVGLTSYKH RHSGLVNVPE EPIEEEEEEE EEEEEEAAQD
MDADDRVVVE YHQELPAGKP ARERSASRRS SASSSDSDEM DYDLELKMIS TPSPKKSMKM
TMYADEVESQ LKNIRNSMRA DSISTSNIKN RIGNKLPSEK FADVRHLLDE KRQHSHSRPP
VSNTKSDIRQ RLGKRPYSPE KAFSSNPVVR REPFSDVHSR LGIPRQDIKG LYSDTREKRS
GSLWTRLGSA PKTKEKNMKK VEHRTPGTEE DDSELQRAWG ALIKEKEQSR QKKSRLDNLP
SLQIEVSRES SSGSEAES
//
