ID   G3SRK8_LOXAF            Unreviewed;      1123 AA.
AC   G3SRK8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=Trafficking protein particle complex subunit 11 {ECO:0000256|ARBA:ARBA00021520};
GN   Name=TRAPPC11 {ECO:0000313|Ensembl:ENSLAFP00000002527.3};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000002527.3, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000002527.3, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000002527.3,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000002527.3}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000002527.3};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- FUNCTION: Involved in endoplasmic reticulum to Golgi apparatus
CC       trafficking at a very early stage. {ECO:0000256|ARBA:ARBA00001995}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network
CC       {ECO:0000256|ARBA:ARBA00004222}.
CC   -!- SIMILARITY: Belongs to the TRAPPC11 family.
CC       {ECO:0000256|ARBA:ARBA00007051}.
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DR   AlphaFoldDB; G3SRK8; -.
DR   STRING; 9785.ENSLAFP00000002527; -.
DR   Ensembl; ENSLAFT00000003032.3; ENSLAFP00000002527.3; ENSLAFG00000003032.3.
DR   eggNOG; KOG4386; Eukaryota.
DR   GeneTree; ENSGT00390000006550; -.
DR   InParanoid; G3SRK8; -.
DR   OMA; CVEYYRD; -.
DR   TreeFam; TF314022; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0030008; C:TRAPP complex; IEA:Ensembl.
DR   GO; GO:0045054; P:constitutive secretory pathway; IEA:Ensembl.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IEA:Ensembl.
DR   GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR   GO; GO:0061635; P:regulation of protein complex stability; IEA:Ensembl.
DR   InterPro; IPR021773; TPC11.
DR   InterPro; IPR025876; TRAPPC11_C.
DR   PANTHER; PTHR14374; FOIE GRAS; 1.
DR   PANTHER; PTHR14374:SF0; TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11; 1.
DR   Pfam; PF11817; Foie-gras_1; 1.
DR   Pfam; PF12742; Gryzun-like; 1.
PE   3: Inferred from homology;
KW   ER-Golgi transport {ECO:0000256|ARBA:ARBA00022892};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          264..521
FT                   /note="Trafficking protein particle complex subunit 11"
FT                   /evidence="ECO:0000259|Pfam:PF11817"
FT   DOMAIN          1037..1095
FT                   /note="Trafficking protein particle complex subunit 11 C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12742"
SQ   SEQUENCE   1123 AA;  127816 MW;  44AC58883AC22C4E CRC64;
     MSPTQWDFPV ELCCRPMAFV TLTGLDVVYN AVHRAVWDAF CANRRADRVP ISFKVLPGDH
     EYPKCRPKRT SYEWYIPKGI LKTGWMNKHL NLVPALVVVF YELDWDEPQW KEKQSECATR
     VEIVRQSLQG RNTKVAVVLI QKKTPLPPGE DVIASERAAA LCNACELSGK SLFVLPHTDH
     LVGYIIRLEN AFYEHAQTYY YTEIRRVKSH KEFLNKTTHQ LLFVRHQFKI AFFSELKQDT
     QNALKNYRTA YNLVHELRAH ETNILEIKTM AGFINYKICR LCFQHNTPLD AIAQFRKHID
     LCKKRIGSAE LSFEHAAWMS KQFQAFGDLF DEAIKLGLTA IQTQNPGFYY QQAAYYAQER
     KQLTETLCDH EATVIYPSPD PLETQTGVLD FYGQRSWRQG VLSFDLSDPE KEKVGVLAIQ
     LKERSIVHSE IIITLLSNAV AQFKKYKCPR MKSHLMVQMG EEYYYAKDYT KALKLLDYVM
     CDYRSEGWWT LLTSILTTAL KCAYLMAQLK GYITYSLELL GRASTLKDEQ KSRIEKNLIN
     VLMNESPEPE PDCDVLAVKT AQKLWADRVS LAGSNVFTIG VQDFVPFVQC KARFHAPSFH
     VDVPVQFDVY LKADCPHPIR FSKLRVSFNN QEYNQFCVIE EASKAGEVLE NLNQEKMCFV
     PGKTRKYLFK FVAKTEDVGK KIEITSVDLI LGHETGRCVV LNWQGGGGDA ASSQEALQAS
     RSFKRRPKLP DNEPHWDSIV IQASTMIISR VPNISVHLRH EPPALTNEMY CLVVTVESHE
     EIQIRDVKLT AGLKPGQDAN LTQKTHVTLH GAELCDESQP ALLTDVPVGE LHPGEQLEKM
     LYVRCGTVGS RMFLVYVSYL INTTVEGKEI VCKCHKDETV TIETVFPFDV AVKFVSTKFE
     HLERVCADIP FLLMADILSA SPWALTVVSS ELQLAPSVTP VDQLESQVDR VVLQTGESAS
     ECFCLRCPSV GNVEGGVATG RYIISWKRTS AMGDTPVIST VITLPHVIIE NIPLHVNADL
     PSFGRVRESL PVRYHLQNKT SLVQDVEVSV EPSDAFMFSG LKQIRLRILP GTEQEMLYNF
     YPLMAGYQQL PSLNVNLLRF PSFTNQLLRR FIPTSIFVKV RYR
//