ID   G3SVC6_LOXAF            Unreviewed;       143 AA.
AC   G3SVC6;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=TNF family profile domain-containing protein {ECO:0000259|SMART:SM00207};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000004188.3, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000004188.3, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000004188.3,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000004188.3}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000004188.3};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the tumor necrosis factor family.
CC       {ECO:0000256|ARBA:ARBA00008670}.
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DR   AlphaFoldDB; G3SVC6; -.
DR   STRING; 9785.ENSLAFP00000004188; -.
DR   Ensembl; ENSLAFT00000005004.3; ENSLAFP00000004188.3; ENSLAFG00000005005.3.
DR   eggNOG; ENOG502ST4X; Eukaryota.
DR   GeneTree; ENSGT00390000015127; -.
DR   HOGENOM; CLU_091735_0_0_1; -.
DR   InParanoid; G3SVC6; -.
DR   OMA; TTHNTSC; -.
DR   TreeFam; TF336384; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005125; F:cytokine activity; IEA:InterPro.
DR   GO; GO:0005164; F:tumor necrosis factor receptor binding; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   Gene3D; 2.60.120.40; -; 1.
DR   InterPro; IPR006052; TNF_dom.
DR   InterPro; IPR042338; TNFSF4.
DR   InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR   PANTHER; PTHR17534; OX40 LIGAND; 1.
DR   PANTHER; PTHR17534:SF4; TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 4; 1.
DR   SMART; SM00207; TNF; 1.
DR   SUPFAM; SSF49842; TNF-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT   DOMAIN          6..133
FT                   /note="TNF family profile"
FT                   /evidence="ECO:0000259|SMART:SM00207"
SQ   SEQUENCE   143 AA;  16166 MW;  2B5DACDE53FB0B06 CRC64;
     PAQYPPIQSI RVQFTRCDNE KGFILTSPNN QETMKVQDNS IIISCDGFYL ISLKGYFSQE
     VSLSLLYRKG REPLLPLTKV KFIDTVTVAY LAFKDKVYLN LTSHNTSCED IQVNGGELIL
     IHQNPGEFCV HTSLEKTLNG HLL
//