ID G3T3H9_LOXAF Unreviewed; 608 AA.
AC G3T3H9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Synaptotagmin like 3 {ECO:0000313|Ensembl:ENSLAFP00000007811.3};
GN Name=SYTL3 {ECO:0000313|Ensembl:ENSLAFP00000007811.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000007811.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000007811.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000007811.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000007811.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000007811.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3T3H9; -.
DR STRING; 9785.ENSLAFP00000007811; -.
DR Ensembl; ENSLAFT00000009320.3; ENSLAFP00000007811.3; ENSLAFG00000009320.3.
DR eggNOG; KOG1028; Eukaryota.
DR GeneTree; ENSGT00940000160610; -.
DR HOGENOM; CLU_002711_0_0_1; -.
DR InParanoid; G3T3H9; -.
DR OMA; RKKKCNP; -.
DR TreeFam; TF341184; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0005544; F:calcium-dependent phospholipid binding; IEA:Ensembl.
DR GO; GO:0042043; F:neurexin family protein binding; IEA:Ensembl.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006887; P:exocytosis; IEA:Ensembl.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR CDD; cd04020; C2B_SLP_1-2-3-4; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR041282; FYVE_2.
DR InterPro; IPR010911; Rab_BD.
DR InterPro; IPR043567; SYTL1-5_C2B.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45716; BITESIZE, ISOFORM I; 1.
DR PANTHER; PTHR45716:SF1; SYNAPTOTAGMIN-LIKE PROTEIN 3; 1.
DR Pfam; PF00168; C2; 2.
DR Pfam; PF02318; FYVE_2; 1.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS50916; RABBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT DOMAIN 4..123
FT /note="RabBD"
FT /evidence="ECO:0000259|PROSITE:PS50916"
FT DOMAIN 305..433
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 459..585
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 146..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 200..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..228
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..249
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 608 AA; 68567 MW; 2AEF2A8AED65E20B CRC64;
MAQEVNLNSL KDLEREVILQ VLYRDQAVQN VEEERIRKLK THLQHLRWKG AKSTNQDYRE
KSCARCQRAL GLLLNRGAVC RGCSYRVCAQ CRVFLRKTHA WKCTVCFEDR NVKIKSGQWF
FEERAKKFPT EGKHRTAGAK LLQSYQKPSK ISVVPPTPPP HSENQCGSQT GLQELGQFKG
FNKSVENLFL SVTTHMKKLS KSQNDMTSDK HHLATGHRQS KGRSERRSQS DTAINVTTRK
VSSPDILKSL NQEDSKHSPD PVSKQQDSSS NPAARPLFSG ELRHGSLISI NSTCTEMGNF
DNANVTGEIE FAIRYCFKTH SLEICIKACK NLAYGEEKKK KCNPYIKIYL LPDRSSQGKR
KTRVQKNTTD PIFQETLKLN ISADTSIFLQ APVNQWQTNN WAQGNFKNQV VLLNFYDYRR
GILSNIKLYD LLKAETCEDS VPHNNGELAL RAKLVLPSGP RKLPEAQEGT DDQPPLNGQL
CLVVLGAKNL PVRSDGTLNS FVKGCLTLPN QQKLRLKSPV LKKQACPQWK HSFVFSGVTT
SQLRQSSLEL TVWDQAIFGM NDRLLGGARL GSKEEPASGT DSCSPSKLQW QKVLSNPNLW
TDMTLVLH
//
