ID G3TAY2_LOXAF Unreviewed; 400 AA.
AC G3TAY2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Decaprenyl diphosphate synthase subunit 2 {ECO:0000313|Ensembl:ENSLAFP00000011079.3};
GN Name=PDSS2 {ECO:0000313|Ensembl:ENSLAFP00000011079.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000011079.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000011079.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000011079.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000011079.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000011079.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR RefSeq; XP_003404360.1; XM_003404312.2.
DR AlphaFoldDB; G3TAY2; -.
DR STRING; 9785.ENSLAFP00000011079; -.
DR Ensembl; ENSLAFT00000013244.3; ENSLAFP00000011079.3; ENSLAFG00000013247.3.
DR GeneID; 100659486; -.
DR KEGG; lav:100659486; -.
DR CTD; 57107; -.
DR eggNOG; KOG0776; Eukaryota.
DR GeneTree; ENSGT00940000153498; -.
DR HOGENOM; CLU_014015_3_1_1; -.
DR InParanoid; G3TAY2; -.
DR OMA; HEQVRWT; -.
DR OrthoDB; 2899987at2759; -.
DR TreeFam; TF354277; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:1990234; C:transferase complex; IEA:Ensembl.
DR GO; GO:0097269; F:all-trans-decaprenyl-diphosphate synthase activity; IEA:Ensembl.
DR GO; GO:0052923; F:all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity; IEA:Ensembl.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
DR GO; GO:0000010; F:trans-hexaprenyltranstransferase activity; IEA:Ensembl.
DR GO; GO:0021549; P:cerebellum development; IEA:Ensembl.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0050878; P:regulation of body fluid levels; IEA:Ensembl.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:Ensembl.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR PANTHER; PTHR12001:SF55; ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 400 AA; 44005 MW; 7F803B1C6272568B CRC64;
MSLRQLLLGF PRSLGASSST RRLWWSPSLD TISSVDSWRG QPSRSRAHWN QVVSEAEKIV
GYPTSFMSLR CLLSDELSNI AMQVRKLVGT QHPLLTTARR LVHDSRNNLQ LRGLVVLLIS
KAAGPSSVDA SCQNYDMVSG IYACQRSLAE ITELIHTALL VHRGIVNLNE LQSSDGPLKD
MQFGNKIAIL SGDFLLANAC NGLALLQNTK VVELIASALM DLVQGVYHEN CTSAKDNHIT
DDIGISTWKE QTFLSHGALL AKSCQAAMEL AKHDAEVQGM AFQYGKHMAM SHKINSDLQP
FIKEKTSDSM AFNLNSAPVV LHQEFLGRDS WIKQIGEAQE KGRLDYAKLR ETIKAGKGVT
SAIDLCRCHG NKALEALESF PPSEARSALE NIVFAVTRFS
//
