ID G3TBS6_LOXAF Unreviewed; 2047 AA.
AC G3TBS6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=PHD finger protein 3 {ECO:0000313|Ensembl:ENSLAFP00000011454.3};
GN Name=PHF3 {ECO:0000313|Ensembl:ENSLAFP00000011454.3};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000011454.3, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000011454.3, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000011454.3,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000011454.3}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000011454.3};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_003404454.1; XM_003404406.2.
DR STRING; 9785.ENSLAFP00000011454; -.
DR Ensembl; ENSLAFT00000013687.3; ENSLAFP00000011454.3; ENSLAFG00000013686.3.
DR GeneID; 100662991; -.
DR KEGG; lav:100662991; -.
DR CTD; 23469; -.
DR eggNOG; KOG1634; Eukaryota.
DR GeneTree; ENSGT00940000155080; -.
DR HOGENOM; CLU_001663_0_0_1; -.
DR InParanoid; G3TBS6; -.
DR OMA; FEAGNTC; -.
DR OrthoDB; 5406765at2759; -.
DR TreeFam; TF350578; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd15638; PHD_PHF3; 1.
DR CDD; cd21548; SPOC_PHF3; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11477:SF10; PHD FINGER PROTEIN 3; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF07744; SPOC; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 717..772
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 930..1049
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 143..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 322..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 462..505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..685
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 860..929
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1081..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1174..1195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1359..1399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1550..1571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1603..1634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1650..1732
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1771..1807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1895..2047
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..640
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 665..680
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..879
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..911
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1085..1112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1605..1634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1662..1677
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1678..1708
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1709..1732
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1778..1807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1896..2047
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2047 AA; 229397 MW; F6B078B630BBBBCA CRC64;
MDIVDTFNHL IPTEHLDDAL FLGSNLENEV CEDFSTSQNV LEDSLKNMLS DKDPMLGSAS
NQFCLPVLDS NDPNFQMPCS TVVGLDDIMD EGVVKESGND TIDEEELILP NRNLRDKVEE
NSVRSPRKSP RLMAQEQVRS LRQSTIAKRS NAAPLSSTKK ASGKTVSAPK AGLRQPERCQ
IKEEVCALLK PEYHKESRRS SRHIGQIEAV PEESVSSGHS SASSCLEMKD EAELGSKHEC
NNQGEANMPS HELSCPLLPE TCVSIEEKKN EALMECKIKT VSSPLFKFSD KEEHEQNDSI
SDKRDKTVVD EMRAKGKIEQ ESKGTVKLSN EGDQVVEEPG SSAVLSGDTA CTNANKTEKN
LEGLSTSVGE ATECNLELKN TMEVTDTAKN SLLRNKIEPL GYCKDTESSD KQLQSTEFNK
PDLEIVSTTD FEPESNILES AIRDASDQNA NQHVESIKTE PHEAADLQAG RNSQSSSVSC
SETKSMKSKH SKPAIHPKQN VTTDTPKKII AAKHEVLHNK NKVNVKSVKR NADEPESQQN
FHRPVKVRKK QVDKDLKIQS SNSGVKSAKS QTHLLFKKTS QDQNLLQISK PLPHSLTDKP
HGYPACSKEP NPPAQSGHLL HSSQKQCHKP QQQAPTMKTN SHVKEELEHA GIEHFKEEDK
LRLKKTEKNL QPRQRRSSKS FSLDEPPLFI PDNIATVKRE GSDHSSSFEN KYVWTPSKQC
GFCKKPHGNR FMVGCGRCDD WFHGDCVGLS LSQAQQMGEE DKEYVCVKCC AEEDKKTEIL
DPDILENQAK VEIHSEDKTM ECEKLGLSKH TPTNEKSKYV DDTVKHKVKI LKRESGEGKN
SSECRDSEIK KWQLAPVRKM GQPVLPRRSS EEKSEKITKE STTIICTGEK ASKPGTHEKQ
EIKKKKIDKG GVSNVHPPAA STSKPSADQI RQSVRHSLKD ILMKRLTDSN LKVPEEKAAK
VATKIEKELF SFFRDTDAKY KNKYRSLMFN LKDPKNSILF KKVLKGEVTP DHLIRMSPEE
LASKELAAWR RRENRHTIEM IEKEQREVER RPITKITHKG EIEIESDAPM KEQEAAMEIQ
EPAANKSLEK TEESEKQKEE IDSMSKDTTS QHRQHLFDLN CKICIGRMAP PVDDLSPKKV
KVVVGVSRKH SDNEAESIAD ALSSTSNILA SEFFEDEKQE SPKSTFSPAP RPEMPGTVEV
ESTFLARLNF IWKGFINMPS VAKFVTKAYP VSGSPEYLTE DLPDSIQVGG RISPQTVWDY
VEKIKASGTK EICVVRFTPV TEEDQISYTL LFAYFSSRKR YGVAANNMKQ VKDMYLIPLG
ATDKIPHPLV PFDGPGLELH RPNLLLGLII RQKLKRQHSA SASASTGHTA EAPESVPMAL
PPDKKSKIEV STEEAPEEEN DFFNSFTTVL HKQRNKPQPT LQEDLPTAIE PLVEVTKQEP
PKPLRFLPGV LIGWENQAST LELANKPLPV DDILQSLLGS TGQVYEQAQP AVEQNTVKEI
PFISEQTNPK AEKIDKVEEV AGGEAKEVKV KVDNHSEATG NSVVVEEEVS VPVSSSVSPG
PLTNLSLRGK PPDISTEAFL TNLSIQSKQE ETVDSKERTL KRQLLQDQES NSQDNRTSNT
GSPGRSNVGK GNIDGSVSCS DNLVANTTRS PQFINLKRDP RQAAGRSQQI STSESKDGDS
CRNGEKHALP GLSHNKEHLT EQTSVDEKSS ALEKNSCVQQ SDNSSVPQNS APVENIHTSQ
TEQAKPLQED ILMQNIETVH LLRRGSAAAP SHFEGGNTCQ PEFPSKSINF TSRSTSPRTN
ANFSPVRPQQ PNLQHLKSSP PAFPFPGPPN FPPQNMFGFP PHLPPPLLPP PGFGFPQNPM
VPWPPVVHLA GQPQRMLGPL SQASRFIGPQ SFYQVKDIRR PERRHSDPWG RQDQQQLDRA
FNRGKGDRQR FYSDSHHLKR ERHEKEWEQE SERHRRRDRN QDKDRDRKSK EEGHKDKERA
RLSHGDRGAD GKASRDGRNV DKKPDKPKSE DHEKDKEREK SKHREGEKDR DRYHKDRDHI
DRAKSKR
//
