ID G3TMK2_LOXAF Unreviewed; 971 AA.
AC G3TMK2;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=MLLT6, PHD finger containing {ECO:0000313|Ensembl:ENSLAFP00000016350.2};
GN Name=MLLT6 {ECO:0000313|Ensembl:ENSLAFP00000016350.2};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000016350.2, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000016350.2, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000016350.2,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000016350.2}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000016350.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; G3TMK2; -.
DR Ensembl; ENSLAFT00000022251.2; ENSLAFP00000016350.2; ENSLAFG00000022685.2.
DR GeneTree; ENSGT00940000158572; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15709; ePHD_AF17; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR PANTHER; PTHR13793:SF90; PROTEIN AF-17; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 1..118
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 54..117
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 223..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 328..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 930..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 637..671
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 233..248
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..306
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..754
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 930..947
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 971 AA; 100256 MW; CAC33F606C6E9CFC CRC64;
RCELCPHKDG ALKRTDNGGW AHVVCALYIP EVQFANVLTM EPIVLQYVPH DRFNKTCYIC
EEQGRESKAA SGACMTCNRH GCRQAFHVTC AQMAGLLCEE EVLEVDNVKY CGYCKYHFSK
MGMSRPVSYC VEGVGFGRLR LGRLASTWRW WGGRMTGATA GNSAMRGGRI LRGPWPGTQG
QFMETHSPCG SSSLLIPLSS TGPALLGPSG YFLAYSMVSS SGSSSSHHEA SSQETSESSR
DSKGKKSSSH SLSHKGKKLS SGKASSLQSS PDFSAFPKLE QPEEDKYSKP TAPTPSAPPS
PSAPEPPKAD LFEQKVVFSG FGPIMRFSTT TSSSGRARAP SPGDYKSPHV AGSGPSAGTH
KRMPTLSAAP APAEEIPETG LKEKKHKASK RSRHGPGRPK GSRNKEGTGG PAVPSLPSAQ
LAGFTATAAS PFSGGSLVSS GLGGLASRTF GPSGSLPSLS LESPLLGAGI YTSNKDPISH
GGGMLRAVCS TPLSSSLLGP PGTSALPRLS RSPFTSTLPS SSASISTTQV FSLAGSTFSL
PSTHIFGTPM GAVNSLLTQA ESSHTEPDLE DCSFRCRGTS PQESLSSMSP ISNLPALFDQ
TASAPCGSGQ LDPAAPGTTN MEQLLEKQSD GEAGVNIVEM LKALHALQKE NQRLQEQILS
LTAKKERLQI LNVQLSVPFP ALPTALPAAN GPVPGPYGLP PQAGSNDSLS TSKSPPGKNS
LGLDNSLSTS SEDPHSGCPS RSSSSLSFHS QPQNGLGRAA GAAGLGAMPM AEGLLGGLAG
SGALPLNGLL GGLNGAAAPN PAGLSQAGGA PTLQLPGCLN SLTEQQRHLL QQQEQQLQQL
QQLLASPQLT PEHQTVIYQM IQQIQQKREL QRLQMAGGSQ LPMASLLAGS STPLLSAGTP
GLLPTASAPP LLPAGALVAP SLGNNTSLMG GPPVLTAQTN PFLSLSGADG SGSGPKGGTT
DKGASANQEK G
//
