ID G3TPA5_LOXAF Unreviewed; 203 AA.
AC G3TPA5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=MORN repeat-containing protein 4 {ECO:0000256|ARBA:ARBA00039855};
GN Name=MORN4 {ECO:0000313|Ensembl:ENSLAFP00000017198.2};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000017198.2, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000017198.2, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000017198.2,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000017198.2}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000017198.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Plays a role in promoting axonal degeneration following
CC neuronal injury by toxic insult or trauma.
CC {ECO:0000256|ARBA:ARBA00037780}.
CC -!- SUBUNIT: Interacts with MYO3A. {ECO:0000256|ARBA:ARBA00038723}.
CC -!- SUBCELLULAR LOCATION: Cell projection, filopodium tip
CC {ECO:0000256|ARBA:ARBA00004495}. Cell projection, stereocilium
CC {ECO:0000256|ARBA:ARBA00004645}.
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DR AlphaFoldDB; G3TPA5; -.
DR STRING; 9785.ENSLAFP00000017198; -.
DR Ensembl; ENSLAFT00000021674.2; ENSLAFP00000017198.2; ENSLAFG00000022767.2.
DR eggNOG; KOG0231; Eukaryota.
DR GeneTree; ENSGT00730000111173; -.
DR HOGENOM; CLU_116793_0_0_1; -.
DR InParanoid; G3TPA5; -.
DR TreeFam; TF323893; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0032433; C:filopodium tip; IEA:UniProtKB-SubCell.
DR GO; GO:0032426; C:stereocilium tip; IEA:Ensembl.
DR GO; GO:0048678; P:response to axon injury; IEA:Ensembl.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 2.
DR InterPro; IPR003409; MORN.
DR PANTHER; PTHR46614; MORN REPEAT-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46614:SF1; MORN REPEAT-CONTAINING PROTEIN 4; 1.
DR Pfam; PF02493; MORN; 4.
DR SMART; SM00698; MORN; 3.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 62..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 203 AA; 21957 MW; 406AA5CC182DD58F CRC64;
RRASAGPMGS GVATGCLGNS QWATGTVPSV AARDGGVKWA RHWWRLCRAP CLGKARRSKG
LGLWSPAPGR DGHPERQSPG RRHGFGQLMF ADGGTYLGHF ENGLFNGFGV LTFSDGSRYE
GEFAQGKFNG VGVFIRHDNM TFEGEFKNGR VDGFGLLTFP DGSHGIPRNE GLFENNKLLR
REKCSAVVQR AQSASKSARN LTA
//
