ID G3TRP6_LOXAF Unreviewed; 148 AA.
AC G3TRP6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Lysozyme B {ECO:0000313|EMBL:CDM98842.1};
DE SubName: Full=Lysozyme like 6 {ECO:0000313|Ensembl:ENSLAFP00000018254.1};
GN Name=LYZL6 {ECO:0000313|Ensembl:ENSLAFP00000018254.1};
GN Synonyms=LYZB {ECO:0000313|EMBL:CDM98842.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000018254.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000018254.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000018254.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDM98842.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26484105; DOI=10.1016/j.gdata.2014.08.003;
RA Premzl M.;
RT "Third party annotation gene data set of eutherian lysozyme genes.";
RL Genom Data 2:258-260(2014).
RN [3] {ECO:0000313|EMBL:CDM98842.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=26862561; DOI=10.1016/j.dib.2015.11.056;
RA Premzl M.;
RT "Curated eutherian third party data gene data sets.";
RL Data Brief 6:208-213(2016).
RN [4] {ECO:0000313|EMBL:CDM98842.1}
RP NUCLEOTIDE SEQUENCE.
RX DOI=10.1016/j.genrep.2019.100414;
RA Premzl M.;
RT "Eutherian third-party data gene collections.";
RL Gene Rep 16:100414-100414(2019).
RN [5] {ECO:0000313|Ensembl:ENSLAFP00000018254.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000018254.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 22 family.
CC {ECO:0000256|RuleBase:RU004440}.
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DR EMBL; HG931841; CDM98842.1; -; Genomic_DNA.
DR RefSeq; XP_003414557.1; XM_003414509.1.
DR STRING; 9785.ENSLAFP00000018254; -.
DR Ensembl; ENSLAFT00000037294.1; ENSLAFP00000018254.1; ENSLAFG00000029877.1.
DR GeneID; 100658694; -.
DR KEGG; lav:100658694; -.
DR CTD; 57151; -.
DR eggNOG; ENOG502SCGK; Eukaryota.
DR GeneTree; ENSGT00940000161690; -.
DR HOGENOM; CLU_111620_1_1_1; -.
DR OMA; EWRLHCA; -.
DR OrthoDB; 5344399at2759; -.
DR TreeFam; TF324882; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0097225; C:sperm midpiece; IEA:Ensembl.
DR GO; GO:0097524; C:sperm plasma membrane; IEA:Ensembl.
DR GO; GO:0003796; F:lysozyme activity; IEA:InterPro.
DR GO; GO:0042742; P:defense response to bacterium; IEA:Ensembl.
DR GO; GO:0007342; P:fusion of sperm to egg plasma membrane involved in single fertilization; IEA:Ensembl.
DR CDD; cd16897; LYZ_C; 1.
DR Gene3D; 1.10.530.10; -; 1.
DR InterPro; IPR001916; Glyco_hydro_22.
DR InterPro; IPR019799; Glyco_hydro_22_CS.
DR InterPro; IPR000974; Glyco_hydro_22_lys.
DR InterPro; IPR023346; Lysozyme-like_dom_sf.
DR PANTHER; PTHR11407; LYSOZYME C; 1.
DR PANTHER; PTHR11407:SF9; LYSOZYME-LIKE PROTEIN 6; 1.
DR Pfam; PF00062; Lys; 1.
DR PRINTS; PR00137; LYSOZYME.
DR PRINTS; PR00135; LYZLACT.
DR SMART; SM00263; LYZ1; 1.
DR SUPFAM; SSF53955; Lysozyme-like; 1.
DR PROSITE; PS00128; GLYCOSYL_HYDROL_F22_1; 1.
DR PROSITE; PS51348; GLYCOSYL_HYDROL_F22_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..148
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015091553"
FT DOMAIN 94..112
FT /note="Glycosyl hydrolases family 22 (GH22)"
FT /evidence="ECO:0000259|PROSITE:PS00128"
SQ SEQUENCE 148 AA; 16713 MW; 579A76EB5C7479B5 CRC64;
MTTALLISLV SCLLAINQAI IMHRCDVAKL LYKEDLHGFE GYPLSAWLCL AFVESKFNTS
KIKENADGSF DYGIFQINSH YWCNDYLSHS ENLCHTDCIE LLNPDLLSTV NCVKKIMSGG
GGLNNWIEWK LHCSGRPLSY WMTGCRLA
//
