ID G3TXF1_LOXAF Unreviewed; 593 AA.
AC G3TXF1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=Syntaxin-binding protein 2 {ECO:0000256|ARBA:ARBA00040518};
DE AltName: Full=Protein unc-18 homolog 2 {ECO:0000256|ARBA:ARBA00042595};
DE AltName: Full=Protein unc-18 homolog B {ECO:0000256|ARBA:ARBA00042592};
GN Name=STXBP2 {ECO:0000313|Ensembl:ENSLAFP00000020259.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000020259.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000020259.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020259.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000020259.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020259.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the STXBP/unc-18/SEC1 family.
CC {ECO:0000256|ARBA:ARBA00009884}.
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DR AlphaFoldDB; G3TXF1; -.
DR STRING; 9785.ENSLAFP00000020259; -.
DR Ensembl; ENSLAFT00000025562.1; ENSLAFP00000020259.1; ENSLAFG00000026499.1.
DR eggNOG; KOG1300; Eukaryota.
DR GeneTree; ENSGT00940000160045; -.
DR InParanoid; G3TXF1; -.
DR OMA; KQWPFVS; -.
DR TreeFam; TF313242; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0042582; C:azurophil granule; IEA:Ensembl.
DR GO; GO:0044194; C:cytolytic granule; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0042581; C:specific granule; IEA:Ensembl.
DR GO; GO:0070820; C:tertiary granule; IEA:Ensembl.
DR GO; GO:0030348; F:syntaxin-3 binding; IEA:Ensembl.
DR GO; GO:0001909; P:leukocyte mediated cytotoxicity; IEA:Ensembl.
DR GO; GO:0043312; P:neutrophil degranulation; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.60; -; 1.
DR Gene3D; 3.40.50.1910; -; 1.
DR Gene3D; 3.40.50.2060; -; 1.
DR InterPro; IPR043154; Sec-1-like_dom1.
DR InterPro; IPR043127; Sec-1-like_dom3a.
DR InterPro; IPR001619; Sec1-like.
DR InterPro; IPR027482; Sec1-like_dom2.
DR InterPro; IPR036045; Sec1-like_sf.
DR PANTHER; PTHR11679:SF27; SYNTAXIN-BINDING PROTEIN 2; 1.
DR PANTHER; PTHR11679; VESICLE PROTEIN SORTING-ASSOCIATED; 1.
DR Pfam; PF00995; Sec1; 1.
DR PIRSF; PIRSF005715; VPS45_Sec1; 1.
DR SUPFAM; SSF56815; Sec1/munc18-like (SM) proteins; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Transport {ECO:0000256|ARBA:ARBA00022927}.
SQ SEQUENCE 593 AA; 66605 MW; AB9DA47B39CE5809 CRC64;
YAPGTLPQVL RVEILSGVIR SVKKDGEWKV LIMDHPSMRI LSSCCKMSDI LAEGITIVED
INKRREPIPS LEAIYLLSPT EKSVQALITD FRGTPTFTYK AAHVFFTDTC PEPLFSELGR
SRVAKALKTL KEIHLAFLPY EAQVFSLDAP HSTYNLYCPF RAGERARQLE ALAQQIATLC
ATLQEYPAIR YRKGPEDTAQ LAHAVLAKLN AFKADMPSLG EGPEKTRSQL LIVDRAADPV
SPLLHELTFQ AMAYDLLDIE HDTYRYETTG LSEAREKAVL LDEDDDLWME LRHMHIADVS
KKVTELLKTF CESKRLTTDK ANIKDLSHIL KKMPQYQKEL NKYSTHLHLA DDCMKHFKGS
VEKLCSVEQD LAMGSDAEGE KIKDAMKLIV PVLLDTAVPA YDKIRVLLLY ILLRNGVSEE
NLAKLIQHAN VQAHCSLIRN LEQLGGTVTN PGGSVPSSRL ERKERLEPTY QLSRWTPVIK
DVMEDAVEDR LDRKLWPFVS DPAPTASSQA AISARFGHWH KNKAGVEVRA GPRLIVYVVG
GVAMSEMRAA YEVTRATEGK WEVLIGSSHI LTPTRFLDDL KTLDQKLEDI PLP
//
