ID G3TYV6_LOXAF Unreviewed; 402 AA.
AC G3TYV6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=NFKB activating protein {ECO:0000313|Ensembl:ENSLAFP00000020764.1};
GN Name=NKAP {ECO:0000313|Ensembl:ENSLAFP00000020764.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000020764.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000020764.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020764.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000020764.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000020764.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NKAP family.
CC {ECO:0000256|ARBA:ARBA00009313}.
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DR AlphaFoldDB; G3TYV6; -.
DR Ensembl; ENSLAFT00000031530.1; ENSLAFP00000020764.1; ENSLAFG00000002962.2.
DR GeneTree; ENSGT00940000160787; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR InterPro; IPR040466; NKAP.
DR InterPro; IPR009269; NKAP_C.
DR PANTHER; PTHR13087; NF-KAPPA B ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR13087:SF2; NF-KAPPA-B-ACTIVATING PROTEIN; 1.
DR Pfam; PF15692; NKAP; 1.
DR Pfam; PF06047; Nkap_C; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT DOMAIN 295..392
FT /note="NF-kappa-B-activating protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF06047"
FT REGION 1..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..44
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..179
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..201
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..277
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 402 AA; 45577 MW; 3C1B1FF043420762 CRC64;
MAPVSGSRTP EREASGSGGK RRSLSRSPKP TRAARSPRSH HSRSHSSSRS GDRNGLSQSS
RNQPYRSRSR SRSRERPSGP RGTPFASATS SGYYGGYSRP YGSDKPWPSL LDKEREESLR
QKRLSERERI GELGAPEVWG LSPKNPEPDS DEHTPVEDDE PKKSTSSAST SEEEKKKKKK
SGRSKERLKK RRKKKSSKRK HKKYSDDSDS DSDSETDSSV KVYKSNEDTK RRAKKYKKKK
SKKNRKESSD SSSKDSQEEF LENPWKDRSK PEEPSDLIGP EAPKTLASQD DKPLNYGHAL
LPGEGAAMAE YVKAGKRIPR RGEIGLTSEE IASFECSGYV MSGSRHRRME AVRLRKENQI
YSADEKRALA SFNQEERRKR ENKILASFRE MVYRKTKGKD DK
//
