ID G3UG80_LOXAF Unreviewed; 525 AA.
AC G3UG80;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Maltase-glucoamylase {ECO:0000313|Ensembl:ENSLAFP00000026838.1};
GN Name=MGAM {ECO:0000313|Ensembl:ENSLAFP00000026838.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000026838.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000026838.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000026838.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000026838.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000026838.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00779}.
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DR AlphaFoldDB; G3UG80; -.
DR Ensembl; ENSLAFT00000031666.1; ENSLAFP00000026838.1; ENSLAFG00000021508.2.
DR GeneTree; ENSGT00940000161540; -.
DR HOGENOM; CLU_000631_2_0_1; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0090599; F:alpha-glucosidase activity; IEA:UniProt.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd14752; GH31_N; 1.
DR CDD; cd00111; Trefoil; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR Gene3D; 4.10.110.10; Spasmolytic Protein, domain 1; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR030458; Glyco_hydro_31_AS.
DR InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR017957; P_trefoil_CS.
DR InterPro; IPR000519; P_trefoil_dom.
DR InterPro; IPR044913; P_trefoil_dom_sf.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF63; MALTASE-GLUCOAMYLASE; 1.
DR Pfam; PF13802; Gal_mutarotas_2; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF00088; Trefoil; 1.
DR SMART; SM00018; PD; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR PROSITE; PS00129; GLYCOSYL_HYDROL_F31_1; 1.
DR PROSITE; PS00025; P_TREFOIL_1; 1.
DR PROSITE; PS51448; P_TREFOIL_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361185};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT DOMAIN 57..103
FT /note="P-type"
FT /evidence="ECO:0000259|PROSITE:PS51448"
SQ SEQUENCE 525 AA; 59340 MW; 755FF4A12F644900 CRC64;
KKFTSLEFML SVLLLVVFII TIPIFVLSAR HSLESEGNIE LSCSLPNPGT SASPISAECP
VVNEQERINC IPDQPPTKAT CDQRGCCWNP QGTISVPWCY YSKSHGYQTE DLFSPHTLGF
TVQLRRLPSP SLFGSDVDNV LLTAEYQTSN RFHFKLTDQD KDRYEVPHEH VQPFEGNAPS
SLSYKVEVSK QPFSIKVTRQ SNNRVLFDSS IGPLLFADQF LQLSILLPSA NVYGLGEHVH
QQYRHDMNWK TWPIFARDAF PNEDVKNLYG TQTFFLCLED ASGLSFGVFL MNSNAMDVVV
QPAPAVTYRV IGGILDFYVF LGNTPEQVVQ EYLELIGRPV LPTYWALGFH LSRYDYESLD
NMKEVVERNR AAGLPYDVQH ADIDYMDQRK DFTYDSVNYK GFPEFVKELH NNGQKLVIIV
DPAISNNSST SSPYGPYDRG SDLKIWVNAS DGVTPVVGEV WPGKTVFPDY TNPKCADWWA
NEFQLFHNQV EFDGIWIDMN EVSNFVDGSV SGCSTSHLNY PPFTP
//
