ID G3UYI8_MOUSE Unreviewed; 174 AA.
AC G3UYI8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Ligase III, DNA, ATP-dependent {ECO:0000313|Ensembl:ENSMUSP00000134101.2};
DE Flags: Fragment;
GN Name=Lig3 {ECO:0000313|Ensembl:ENSMUSP00000134101.2,
GN ECO:0000313|MGI:MGI:109152};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000134101.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000134101.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134101.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000134101.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134101.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3UYI8; -.
DR SMR; G3UYI8; -.
DR MaxQB; G3UYI8; -.
DR PeptideAtlas; G3UYI8; -.
DR ProteomicsDB; 361117; -.
DR Antibodypedia; 1860; 372 antibodies from 34 providers.
DR Ensembl; ENSMUST00000172837.2; ENSMUSP00000134101.2; ENSMUSG00000020697.17.
DR AGR; MGI:109152; -.
DR MGI; MGI:109152; Lig3.
DR VEuPathDB; HostDB:ENSMUSG00000020697; -.
DR GeneTree; ENSGT00940000156492; -.
DR HOGENOM; CLU_1543592_0_0_1; -.
DR ChiTaRS; Lig3; mouse.
DR Proteomes; UP000000589; Chromosome 11.
DR Bgee; ENSMUSG00000020697; Expressed in gastrula and 264 other cell types or tissues.
DR ExpressionAtlas; G3UYI8; baseline and differential.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR031916; LIG3_BRCT.
DR Pfam; PF16759; LIG3_BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:G3UYI8,
KW ECO:0007829|MaxQB:G3UYI8};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 127..173
FT /note="DNA ligase 3 BRCT"
FT /evidence="ECO:0000259|Pfam:PF16759"
FT REGION 34..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000134101.2"
SQ SEQUENCE 174 AA; 18669 MW; C56B73471B0E649B CRC64;
RIRDDKDWKS ATNLPQLKEL YQLSKDKADF AVVAGDEASP TTGGSSGENE GTAGSAGPCK
GPPSKSSASA KTTEQKLNSP SSRGGIKPIP KHSPMKPGEK LAVKSSPVKV GMKRKATDET
PCLKKVLLDV FTGVRLYLPP STPDFKRLKR YFVAFDGDLV QEFDMGSATH VLAY
//
