ID G3V5V5_HUMAN Unreviewed; 190 AA.
AC G3V5V5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Kelch domain containing 1 {ECO:0000313|Ensembl:ENSP00000452543.2};
DE Flags: Fragment;
GN Name=KLHDC1 {ECO:0000313|Ensembl:ENSP00000452543.2};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000452543.2, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000452543.2, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12508121; DOI=10.1038/nature01348;
RA Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H.,
RA Du H., Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T.,
RA Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B.,
RA Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D.,
RA Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R.,
RA Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S.,
RA Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C.,
RA Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S.,
RA Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C.,
RA Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P.,
RA Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J.,
RA Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F.,
RA Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F.,
RA Waterston R., Hood L., Weissenbach J.;
RT "The DNA sequence and analysis of human chromosome 14.";
RL Nature 421:601-607(2003).
RN [2] {ECO:0000313|Ensembl:ENSP00000452543.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL591767; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; G3V5V5; -.
DR SMR; G3V5V5; -.
DR MassIVE; G3V5V5; -.
DR PeptideAtlas; G3V5V5; -.
DR Antibodypedia; 10289; 105 antibodies from 17 providers.
DR Ensembl; ENST00000553274.1; ENSP00000452543.2; ENSG00000197776.8.
DR UCSC; uc059bgf.1; human.
DR HGNC; HGNC:19836; KLHDC1.
DR VEuPathDB; HostDB:ENSG00000197776; -.
DR GeneTree; ENSGT00940000157509; -.
DR HOGENOM; CLU_123110_0_0_1; -.
DR ChiTaRS; KLHDC1; human.
DR Proteomes; UP000005640; Chromosome 14.
DR Bgee; ENSG00000197776; Expressed in calcaneal tendon and 168 other cell types or tissues.
DR ExpressionAtlas; G3V5V5; baseline and differential.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR PANTHER; PTHR46228; KELCH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46228:SF1; KELCH DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13418; Kelch_4; 1.
DR Pfam; PF13854; Kelch_5; 1.
DR SUPFAM; SSF117281; Kelch motif; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT NON_TER 190
FT /evidence="ECO:0000313|Ensembl:ENSP00000452543.2"
SQ SEQUENCE 190 AA; 22104 MW; DD9CB7DEFF3FCE24 CRC64;
MADSQLFCVA EERSGHCAVV DGNFLYVWGG YVSIEDNEVY LPNDEIWTYD IDSGLWRMHL
MEGELPASMS GSCGACINGK LYIFGGYDDK GYSNRLYFVN LRTRDETYIW EKITDFEGQP
PTPRDKLSCW VYKDRKSRYS GDGIMMSTYL TQRHRLGFNQ KLKVEFHHSH EPRIHVQFLE
IRVISLADVF
//
