ID G3VD43_SARHA Unreviewed; 612 AA.
AC G3VD43;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=RalA binding protein 1 {ECO:0000313|Ensembl:ENSSHAP00000001097.2};
GN Name=RALBP1 {ECO:0000313|Ensembl:ENSSHAP00000001097.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000001097.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000001097.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000001097.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3VD43; -.
DR STRING; 9305.ENSSHAP00000001097; -.
DR Ensembl; ENSSHAT00000001112.2; ENSSHAP00000001097.2; ENSSHAG00000000984.2.
DR eggNOG; KOG4370; Eukaryota.
DR GeneTree; ENSGT00940000154639; -.
DR HOGENOM; CLU_028068_1_0_1; -.
DR TreeFam; TF315411; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd04381; RhoGap_RalBP1; 1.
DR Gene3D; 1.20.58.90; -; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR039767; RALBP1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR12783; RALA BINDING PROTEIN 1 RALBP1; 1.
DR PANTHER; PTHR12783:SF5; RALA-BINDING PROTEIN 1; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007648}.
FT DOMAIN 192..380
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..495
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..573
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..612
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 70957 MW; 4BFA9F9A277030CF CRC64;
MTECFLPPTS SPSEHRRVEH GSGLTRTPSS EEISPTKFPG LYRTGEPSPP HDSLHEPPDI
VSDDEKEHGK KKGKFKKKEK RTEGYAAFQE DSSGDEAESP SKMKRSKGIH VFKKPSFSKK
KEKDFKVKEK PKEEKHKEEK HKEEKHKEKK SKDLTAADVV KQWKEKKKKK KPTQEPEMPQ
VDVPSLRPIF GIPVAEAAER TMMYDGIRLP AVFRECIDYV EKYGMKCEGI YRVSGIKSKV
DELKAAFDRE ESPNLEEYEP NTVASLLKQY LRDLPENLLT KELLPRFEEA CGRSTEGEKV
QEFQRLLKEL PECNYLLISW LIVHMDHVIS KELETKMNIQ NISIVLSPTV QISNRVLYVF
FTHVQELFGN VILKQVTKPL RWSNMATMPT LPETQESIKE EIRRQECETK IAQEIASLSK
EDVSKEEMNE NEEVINILLA QENEILTEQE ELLAMEQFLR RQIASEKEEI ERLRAEIAEI
QSRQQHGRSE TEEYSSESES ESEDEEELQV ILEDLQRQNE ELEIKNNHLN QAIHEEREAI
IELRVQLRLL QMQRAKSEQQ VQEDEEPEKR GGGPQQQRDC VPETKAAKEQ QPKAVKEQAK
PSPSKDRKET PI
//
