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Database: UniProt
Entry: G3VQP1_SARHA
LinkDB: G3VQP1_SARHA
Original site: G3VQP1_SARHA 
ID   G3VQP1_SARHA            Unreviewed;       727 AA.
AC   G3VQP1;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-SEP-2017, entry version 45.
DE   SubName: Full=Transient receptor potential cation channel subfamily V member 6 {ECO:0000313|Ensembl:ENSSHAP00000005496};
GN   Name=TRPV6 {ECO:0000313|Ensembl:ENSSHAP00000005496};
OS   Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX   NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000005496};
RN   [1] {ECO:0000313|Ensembl:ENSSHAP00000005496}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA   Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E.,
RA   Miller J., Walenz B., Knight J., Qi J., Zhao F., Wang Q.,
RA   Bedoya-Reina O.C., Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A.,
RA   Woodbridge P., Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S.,
RA   Helgen K.M., Lesk A.M., Pringle T.H., Patterson N., Zhang Y.,
RA   Kreiss A., Woods G.M., Jones M.E., Schuster S.C.;
RT   "Genetic diversity and population structure of the endangered
RT   marsupial Sarcophilus harrisii (Tasmanian devil).";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN   [2] {ECO:0000313|Ensembl:ENSSHAP00000005496}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the transient receptor (TC 1.A.4) family.
CC       {ECO:0000256|SAAS:SAAS00788929}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSSHAP00000005496}.
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DR   EMBL; AEFK01197860; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9305.ENSSHAP00000005496; -.
DR   Ensembl; ENSSHAT00000005550; ENSSHAP00000005496; ENSSHAG00000004802.
DR   eggNOG; KOG3676; Eukaryota.
DR   eggNOG; ENOG4110DG4; LUCA.
DR   GeneTree; ENSGT00550000074425; -.
DR   InParanoid; G3VQP1; -.
DR   OMA; VFEPMTS; -.
DR   OrthoDB; EOG091G0314; -.
DR   TreeFam; TF314711; -.
DR   Proteomes; UP000007648; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR   CDD; cd00204; ANK; 2.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR020683; Ankyrin_rpt-contain_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR004729; TRP_channel.
DR   InterPro; IPR024862; TRPV.
DR   InterPro; IPR008344; TRPV5/TRPV6.
DR   InterPro; IPR008345; TRPV6_channel.
DR   PANTHER; PTHR10582; PTHR10582; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   PRINTS; PR01765; ECACCHANNEL.
DR   PRINTS; PR01766; ECACCHANNEL1.
DR   SMART; SM00248; ANK; 5.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   TIGRFAMs; TIGR00870; trp; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 2.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023,
KW   ECO:0000256|SAAS:SAAS00844120};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007648};
KW   Ion channel {ECO:0000256|SAAS:SAAS00816195};
KW   Ion transport {ECO:0000256|SAAS:SAAS00816776};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|SAAS:SAAS00816535}.
FT   TRANSMEM    326    350       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    423    443       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    449    467       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    488    513       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    554    576       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       44    260       ANK_REP_REGION. {ECO:0000259|PROSITE:
FT                                PS50297}.
FT   REPEAT      116    148       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
FT   REPEAT      160    192       ANK. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00023}.
SQ   SEQUENCE   727 AA;  82748 MW;  8CCFB64A9AB0C6B6 CRC64;
     MGGSSFKMRG TWTHLREILR TWMLREQVWT QSLDEANMLQ QKRIWESPLL KAAKENDLCT
     LKKLVVDGPC DIHQRGALGE TALHIASLYD NLEAAKLLME VAPELVNEPM TSELYAGQTA
     LHMAIVNQNT NLVRALLARG ANISARVTGR AFRQNKLFYF GEHPLSFAAC VGNEEIVRLL
     IEFGANIRAQ DHLGNTVLHI LVLQPGKNFA CQMYNVLLSY DGQGSHLQPL ELISNHQGLT
     PFKLAGVEGN TVMFNHLMQK RKYIQWTHGP LTSTLYDLTD IDSWGDELSF LELIVSTKNR
     QARQILDQTP VKELVNLKWN RFGRPYFYIL GAIYVLYMIC FTMCCVYRPL KPRNDNQTSS
     RDINLFREKC LQESYVTSED YIRLIGELVS VIGAVAILLS EIPDIFRVGF ARYFGRTILG
     GPFHVIIIIY AGLVLVTMVM RLTSTSGEVV PMSFALVLGW CNVMYFARGF QMLGPFTIMI
     QKMIFGDLLR FCWLMAVVIL GFASGGAAFY VIFQTEDPDE LGHFFDYPMA LFSTFELFLT
     IIDGPANYDV DLPFMYSITY AAFAIIATLL MLNLLIAMMG DTHWRVAHER DELWRAQVVA
     TTVMLERKLP RCLWPRSGIC GREYGLGDRW FLRVEDRQDP NRQRIQRYAH AFNPLGTDDL
     DKDSLNKLDL TPPCGHHRLA TATPSISRST TRSSANWERL RRGTLGINLR GEINRGLEEE
     EGRVYQV
//
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