ID G3WD84_SARHA Unreviewed; 2007 AA.
AC G3WD84;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=PHD finger protein 3 {ECO:0000313|Ensembl:ENSSHAP00000013389.2};
GN Name=PHF3 {ECO:0000313|Ensembl:ENSSHAP00000013389.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000013389.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000013389.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000013389.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 9305.ENSSHAP00000013389; -.
DR Ensembl; ENSSHAT00000013500.2; ENSSHAP00000013389.2; ENSSHAG00000011449.2.
DR eggNOG; KOG1634; Eukaryota.
DR GeneTree; ENSGT00940000155080; -.
DR HOGENOM; CLU_001663_0_0_1; -.
DR OrthoDB; 5406765at2759; -.
DR TreeFam; TF350578; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd15638; PHD_PHF3; 1.
DR CDD; cd21548; SPOC_PHF3; 1.
DR Gene3D; 1.10.472.30; Transcription elongation factor S-II, central domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR012921; SPOC_C.
DR InterPro; IPR003618; TFIIS_cen_dom.
DR InterPro; IPR036575; TFIIS_cen_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11477:SF10; PHD FINGER PROTEIN 3; 1.
DR PANTHER; PTHR11477; TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF07744; SPOC; 1.
DR Pfam; PF07500; TFIIS_M; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00510; TFS2M; 1.
DR SUPFAM; SSF46942; Elongation factor TFIIS domain 2; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 722..777
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 935..1004
FT /note="TFIIS central"
FT /evidence="ECO:0000259|PROSITE:PS51321"
FT REGION 204..225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 668..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 900..933
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1029..1075
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1549..2007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..325
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 412..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 668..685
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 900..916
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1550..1568
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1569..1612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1633..1649
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1667..1682
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1683..1700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1713..1779
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1781..1831
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1858..1998
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2007 AA; 226354 MW; 3C4A5D3F14B4E3B2 CRC64;
MIFFLSFYRA ERHTEVFMDI VDTFNHLIPT EHLDDALFLG SNLENEVCED FSTSQNVLED
SLKNMLSDKD PMLGSASNQF CLPVLDSNDP NFQMPCSTVV GLDDIMDEGV VKESGNDTID
EEELILPNRN LRDKVEETSV RSPRKSPRLM AQEQVRSLRQ STIAKRSNTT PLTNSKRAAV
KNASAQKTSV RQLDRCQNKE EGVYTTPKAE VRRSSRHTGL TEEVPEVLTV SSSHLASLPC
HELKDEAKLD IKHKCHKGET PVPSHSLTTS HLSETCSPEE KEDKTKSDSA VFLKLLDKEE
HEHNNPLTSK TDETNLEGKD FNGSIDHTSK ETLRFSREVD QMEIAETATA SSDITSCSTP
NNTEKNNVVL SNSVDEIVEC KTELQDVVET TVKAVPLLQE TTNLLSNLKG TDTKVSDEHS
DITEFNETDL KSEDATANES ESSVLENSIC DPPDQSLQQH AENIKIVSHE IAEIQDDRNS
QSSNTSLYCK TVKSKNTKSL IHSKQNIAAS TQKKIVSAKQ EIHSKTRVGV KSMKRNAEES
QQNFHKPVKV RKKQVDKNLK SQSSGPNIKS VKNQTHTTLK KGSQAQNLVQ TPKLLAHSLS
DKMHGNPGCS KESYHMTSTH TRHLQHSNQK QIHRQQQLSA TMKTNSHVKE DIDYLGLEHI
KEEDKLKVKK AEKNLQPRQR RSSKSFSLDE PPLFIPDNIS TVKREGSEHI SSSENKYMWA
PSKQCGFCKK PHGNRFMVGC GRCDDWFHGD CVGLSLSQAQ QMGEEDKEYV CVKCCAEEDK
KSEPVDSEIL ENQAKIEVHR EDKAMDCEKL GLSKQAPTNE KNKHVDDTTK HKVKILRRES
GDGKNSSEYR DSEIKKWQLA PLRKMGQTIL PRRSSEEKNE KITKESTTVF CTGEKTTKSG
IHEKQDFKKK KTEKTGLPNV HAPPTPASKP SADQIRQSVK HSLKDILMKR LTDSNLKIPE
ERASKVATKI EKELFSFFRD TDAKYKNKYR SLMFNLKDPK NNTIEMIEKE QREVERRPIT
KITHKGEIEI ESDAPMKEQE ETMEMQESTT TKSVEKVEDL EKEEADSLSK DTTSQHKNHL
FDLNCKICIG RMAPPADDLS PKKVKVAVGV ARKHSDNEAE NIADALSSTS NILGSEFFDE
EKQESPKSTF SPAPRPEMPG AVEVESTFLA RLNFIWKGFI NMPSVAKFVI KAYPVSGSPE
YLTEDLPDSI QVGGRISPQT VWDYVEKIKA SGTKEICVVR FTPVTEEDQI SYTLLFAYFS
SRKRYGVAAN NMKQVKDMYL IPLGASDKIP HPLVPFDGPG LELHRPNLLL GLIIRQKMKR
QFTASSSTSH VDETPESIPM TLPPDKKIKI EISNEEEPEE ENDFFNSFTT VLHKQRNKPQ
QASQEEIPAT MEPIVELLKQ EPPKPLRFLP GVLIGWENQP STIDLANKPL PVDDILQSLL
GTTSQVQEQT KSAVEPSASE EIPLITEQMS SKEEKIDGLD IAAGEADDTK IKVNDPPKSA
ENSVVIEDTP IVGTSLQLSG TLPGLTLKGK PPDVSTEAFL TNLSIQSQIE ETEEGKERIS
KKQDQENALQ ENKTLNTSSP TASNGGKGNG DNVGISPENM TANTSRSPQF INLKRDPRQA
AGRNQQITLD SKEGDGSRNE EKKTIPSQSY DKEHTGMILI QPTDPEEKQT SVEKDSHFQQ
SNDSKCEDQQ ITASLENVHT TQTEDTKHLQ DESSMQNIET VHTFRRGPAA TTSSHFEAGN
TSQPEFNSKT TNFTSKSMSP GSSGNFSPVR LQQHNFHPKS SPPGFPFPGP PAFPPQSMFG
YPPHLPPPLL PPPGFGFAQN PMMPWPPIVH LPGQPQHFMG PHAQASRFSG PQNFYPVKDS
RRPERRHSDP WGRQDQQQLD RPFSRGKGDQ QRFYGDSHHL KRERHEKEWE QESERHRRRD
RNQDKERDRK SREEGHKDQE RSRLSHGDRG SDGKSNRDNR NVEKKPDKPK NEDHEKDKER
EKSRHSEKDR DRHHKDRDHI DRAKSKR
//
