GenomeNet

Database: UniProt
Entry: G3WH74_SARHA
LinkDB: G3WH74_SARHA
Original site: G3WH74_SARHA 
ID   G3WH74_SARHA            Unreviewed;      1835 AA.
AC   G3WH74;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   30-AUG-2017, entry version 29.
DE   SubName: Full=Transient receptor potential cation channel subfamily M member 7 {ECO:0000313|Ensembl:ENSSHAP00000014779};
GN   Name=TRPM7 {ECO:0000313|Ensembl:ENSSHAP00000014779};
OS   Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX   NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000014779, ECO:0000313|Proteomes:UP000007648};
RN   [1] {ECO:0000313|Ensembl:ENSSHAP00000014779}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA   Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E.,
RA   Miller J., Walenz B., Knight J., Qi J., Zhao F., Wang Q.,
RA   Bedoya-Reina O.C., Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A.,
RA   Woodbridge P., Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S.,
RA   Helgen K.M., Lesk A.M., Pringle T.H., Patterson N., Zhang Y.,
RA   Kreiss A., Woods G.M., Jones M.E., Schuster S.C.;
RT   "Genetic diversity and population structure of the endangered
RT   marsupial Sarcophilus harrisii (Tasmanian devil).";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN   [2] {ECO:0000313|Ensembl:ENSSHAP00000014779}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSSHAP00000014779}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AEFK01009393; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01009394; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01009395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01009396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01009397; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSSHAT00000014904; ENSSHAP00000014779; ENSSHAG00000012617.
DR   eggNOG; KOG3614; Eukaryota.
DR   eggNOG; ENOG410XR5B; LUCA.
DR   GeneTree; ENSGT00760000119127; -.
DR   Proteomes; UP000007648; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:0006812; P:cation transport; IEA:InterPro.
DR   GO; GO:0010961; P:cellular magnesium ion homeostasis; IEA:InterPro.
DR   GO; GO:0051262; P:protein tetramerization; IEA:InterPro.
DR   Gene3D; 1.20.5.1010; -; 1.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR011009; Kinase-like_dom.
DR   InterPro; IPR004166; MHCK_EF2_kinase.
DR   InterPro; IPR029601; TRPM7.
DR   InterPro; IPR032415; TRPM_tetra.
DR   PANTHER; PTHR13800:SF29; PTHR13800:SF29; 1.
DR   Pfam; PF02816; Alpha_kinase; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF16519; TRPM_tetra; 1.
DR   SMART; SM00811; Alpha_kinase; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   PROSITE; PS51158; ALPHA_KINASE; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007648};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    797    817       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    864    883       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    895    914       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    934    954       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1018   1040       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN     1566   1796       Alpha-type protein kinase.
FT                                {ECO:0000259|PROSITE:PS51158}.
SQ   SEQUENCE   1835 AA;  209023 MW;  A9ED87C3935BEFB8 CRC64;
     MKYSDVKLGE HLNQETEEWS VEKHTEQSPT DSYGVINFQG GSHSYRAKYV RLSYDTKPEI
     ILQLLLKEWQ MELPKLVISV HGGMQKFELH PRIKQLLGKG LIKAAVTTGA WILTGGVNTG
     VAKHVGDALK EHASRSSRKI CTIGIAPWGV IENRNDLVGR DVVAPYQTLL NPLSKLNVLN
     NLHSHFILVD DGTVGKYGAE VRLRRELEKT INQQRIHARI GQGVPVVALI FEGGPNVILT
     VLEYLQESPP VPVVVCEGTG RAADILAHVH KQTEEGGNLP DAAEPDIIST IKKTFNFGQS
     EAVHLFQTLM ECMKKKELIT VFHIGSDEHQ DIDVAILTAL LKGTNASAFD QLVLTLAWDR
     VDIAKNHVFV YGQQWLVGSL EQAMLDALVM DRVAFVKLLI ENGVSMHKFL TIPRLEELYN
     TKQGPTNPML FHLVRDVKQG NLPPGYKITL IDIGLVIEYL MGGTYRCTYT RKRFRVIYNS
     LGGNNRRSGR NTSSSTPQLR KSHESFGNRE DKREKMRHNH FIKTAQPYRP KIDTTVEEGK
     KKRTKDEIVD IDDPETRRFP YPLNELLIWA CLMKRQVMAL FFWQHGEESM AKALVACKMY
     RSMAYEAKQS DLVDDTSEEL KQYSNDFGQL AVELLEQSFR QDETMAMKLL TYELKNWSNS
     TCLKLAVSSR LRPFVAHTCT QMLLSDMWMG RLNMRKNSWY KVILSILVPP AILMLEYKTK
     AEMSHIPQSQ DAHQMTMEDS ENNFQNITEE IPLEIFKEIK VLENNEGKTE LDIQVKPKKL
     PITRKFYAFY HAPIVKFWFN TLAYLGFLML YTFVVLVKME QLPSVQEWIV IAYIFTYAIE
     KIREIFMSEA GKISQKIKVW FSDYFNISDT IAIVTFFIGF GLRFGARWKF GNDKIFVAGR
     LIYCLNIIFW YVRLLDFLAV NQQAGPYVMM IGKMVANMFY IVVIMALVLL SFGVPRQAIL
     YPHEPPSWRL AKDVVFNPYW MIFGEVYAYE IDVCANNSDG SVKSLCGPGT WLTPFLQAVY
     LFVQYIIMVN LLIAFFNNVY LQVKAISNTV WKYQRYHFIM AYHEKPVLPP PLIILSHVAS
     MCCCICKRRK KDKTSNGPKL FLTEEDQKKL HDFEEQCVEM YFNEKDDKFH SGSEERIRVT
     FERVEQMYIQ IKEVGDRVNY IKRSLHSLDS QIGHLQDLSA LTVDTLKTLT AQKASEASKV
     HNEITRELSI SKHLAQNLID DGPVRSSLWK KQCVGNTISS SLPQGGLENN NPFLCNIFIR
     DERDAQCKIT GQDLALIPRR EELISRREGF NFPEAGSSGG ALFPSAIFPP ELRHRVHGAE
     TSKIINKNQK LGSSSNSTPH PSSPPNKFFV STPSQPSCTS QVGNVILDKE HTSSKAAEGD
     AIEFGAFVGH RDSMELQRFK EASYKMKEIL AVNILEQQKD IKKTIPEDVE IPKYQSDLPP
     DNSLKHVSSY AGLTECHKIP ISLHSDQVQN SNRRASAEDT HNVDSKAALL SDWLQDRTAN
     TQMPPEEETA NGIASPFKPV MDINYYYSAV ERNNLMRLSQ SIPFTPVPPR GEPVTVYRLE
     ESSPNILNNS MSSWSQLGLC AKIEFLSKEE MGGGLRRAVK VLCTWSEYEI LKSGHLYIIK
     SFLPDVVNTW SSVYKEDTVL HLCLREIQQQ RAAQKLTFAF NQMKPKSIPY SPRFLEVFLL
     YCHSAGQWFA VEECMTGEFR KYNNNNGDEI IPTNTLEEIM LAFSHWTYEY TRGELLVLDL
     QGVGENLTDP SVIKAGEKRS SDMVFGPANL GEDAIKNFRA KHHCNSCCRK LKLPDLKRND
     YTPDKNLFPQ DDSPDLSVEP GSSTKESPNS IRLML
//
DBGET integrated database retrieval system