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Database: UniProt
Entry: G3WPG8_SARHA
LinkDB: G3WPG8_SARHA
Original site: G3WPG8_SARHA 
ID   G3WPG8_SARHA            Unreviewed;       774 AA.
AC   G3WPG8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-SEP-2017, entry version 34.
DE   SubName: Full=Potassium voltage-gated channel subfamily Q member 5 {ECO:0000313|Ensembl:ENSSHAP00000017323};
GN   Name=KCNQ5 {ECO:0000313|Ensembl:ENSSHAP00000017323};
OS   Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX   NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000017323, ECO:0000313|Proteomes:UP000007648};
RN   [1] {ECO:0000313|Ensembl:ENSSHAP00000017323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA   Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E.,
RA   Miller J., Walenz B., Knight J., Qi J., Zhao F., Wang Q.,
RA   Bedoya-Reina O.C., Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A.,
RA   Woodbridge P., Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S.,
RA   Helgen K.M., Lesk A.M., Pringle T.H., Patterson N., Zhang Y.,
RA   Kreiss A., Woods G.M., Jones M.E., Schuster S.C.;
RT   "Genetic diversity and population structure of the endangered
RT   marsupial Sarcophilus harrisii (Tasmanian devil).";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN   [2] {ECO:0000313|Ensembl:ENSSHAP00000017323}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the potassium channel family.
CC       {ECO:0000256|SAAS:SAAS00692852}.
CC   -!- CAUTION: The sequence shown here is derived from an Ensembl
CC       automatic analysis pipeline and should be considered as
CC       preliminary data. {ECO:0000313|Ensembl:ENSSHAP00000017323}.
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DR   EMBL; AEFK01168202; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01168203; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01168204; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01168205; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01168206; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01168207; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01168208; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01168209; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AEFK01168210; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9305.ENSSHAP00000017323; -.
DR   Ensembl; ENSSHAT00000017468; ENSSHAP00000017323; ENSSHAG00000014723.
DR   eggNOG; KOG1419; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00550000074513; -.
DR   InParanoid; G3WPG8; -.
DR   OMA; RMYTSRK; -.
DR   OrthoDB; EOG091G02ZT; -.
DR   TreeFam; TF315186; -.
DR   Proteomes; UP000007648; Unassembled WGS sequence.
DR   GO; GO:0030118; C:clathrin coat; IEA:Ensembl.
DR   GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:Ensembl.
DR   GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:Ensembl.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR   InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR   InterPro; IPR028325; VG_K_chnl.
DR   PANTHER; PTHR11537; PTHR11537; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF03520; KCNQ_channel; 1.
DR   PRINTS; PR00169; KCHANNEL.
DR   PRINTS; PR01459; KCNQCHANNEL.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007648};
KW   Ion channel {ECO:0000256|SAAS:SAAS00417203};
KW   Ion transport {ECO:0000256|SAAS:SAAS00417186};
KW   Membrane {ECO:0000256|SAAS:SAAS00788393, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|SAAS:SAAS00417282};
KW   Potassium channel {ECO:0000256|SAAS:SAAS00417246};
KW   Potassium transport {ECO:0000256|SAAS:SAAS00417240};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00793138,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00789957,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00417268}.
FT   TRANSMEM      6     23       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     44     61       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    109    128       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    169    194       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        5    194       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      289    477       KCNQ_channel. {ECO:0000259|Pfam:PF03520}.
SQ   SEQUENCE   774 AA;  85905 MW;  7A10A83838350275 CRC64;
     CYLIQEFVMI VVFGLEFIIR IWSAGCCCRY RGWQGRLRFA RKPFCVIDTI VLIASIAVVS
     AKTQGNIFAT SALRSLRFLQ ILRMVRMDRR GGTWKLLGSV VYAHSKELIT AWYIGFLVLI
     FSSFLVYLVE KDANKQFSTY ADALWWGTIT LTTIGYGDKT PLTWLGRLLS AGFALLGISF
     FALPAGILGS GFALKVQEQH RQKHFEKRRN PAASLIQCVW RSYAADEKSV SIATWKPHLK
     ALHTCSPTKK DQGETSSSQK LSFKERVRMA SPRGQSIKSR QASVGDRRSP STDITAESSP
     TKVQKSWSFN DRTRFRPSLR LKSSQPKPVI DADTALGTDD VYDEKGCQCD VSVEDLTPPL
     KTVIRAISRI MKFHVAKRKF KETLRPYDVK DVIEQYSAGH LDMLCRIKSL QTRVDQILGK
     GQITSDKKSR EKNTAELETA DDLSMLGRVV KVEKQVQSIE SKLDCLLDIY QQVLRKGSAS
     ALTLASFQIP PFECEQTSDY QSPVDSKDLS SSAQNSGCLS RSASANISRG LQFILTPNEF
     STQTFYALSP TMHSQATPVP MSQSDGPAMV VTNNITNQIH QVTKPVAPTT LQIPPLPAIK
     HIPKPEPIQI NPATMQESIS DVTACLIASK ESVPSIQSNP TKDRSLRKSF DMGGETLLSV
     RPPVQKDLGK SLSVQNLIRS TEELNVQLSG SDSGGSRGSQ EFYPKWREST LFITDEEVGL
     EETESETLDS ISQPAKETAF PSDSLRTGMS RSSQNICKAG ESPDVLSLPH VKLK
//
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