ID G3WSA5_SARHA Unreviewed; 352 AA.
AC G3WSA5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Arginine-hydroxylase NDUFAF5, mitochondrial {ECO:0000256|ARBA:ARBA00040937};
DE AltName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 {ECO:0000256|ARBA:ARBA00041833};
DE AltName: Full=Putative methyltransferase NDUFAF5 {ECO:0000256|ARBA:ARBA00042549};
GN Name=NDUFAF5 {ECO:0000313|Ensembl:ENSSHAP00000018310.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000018310.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000018310.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000018310.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000256|ARBA:ARBA00008361}.
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DR AlphaFoldDB; G3WSA5; -.
DR STRING; 9305.ENSSHAP00000018310; -.
DR Ensembl; ENSSHAT00000018460.2; ENSSHAP00000018310.2; ENSSHAG00000015542.2.
DR eggNOG; KOG2940; Eukaryota.
DR GeneTree; ENSGT00390000014687; -.
DR HOGENOM; CLU_046586_0_2_1; -.
DR InParanoid; G3WSA5; -.
DR TreeFam; TF315222; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0099617; C:matrix side of mitochondrial inner membrane; IEA:Ensembl.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:Ensembl.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13090:SF1; ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13090; UNCHARACTERIZED; 1.
DR Pfam; PF08241; Methyltransf_11; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..352
FT /note="Arginine-hydroxylase NDUFAF5, mitochondrial"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5029655621"
FT DOMAIN 103..194
FT /note="Methyltransferase type 11"
FT /evidence="ECO:0000259|Pfam:PF08241"
SQ SEQUENCE 352 AA; 38994 MW; 83D1915F0FBC1E0A CRC64;
MLKAVQLRWW RRLVLAALRH GAGCGCGGGG RPSGTRGTSS YRSAFGGAAS GAVNVFDRVL
KRKQKNWAAQ QPEPLKYEYL KEEVGSRVAD RVYDIARDFP LALDVGCGRG YIAQHLNKEV
VGKIFQADIA ENALKNSVET EIPTVRVLAD EEFLPFKENT FDLVVSSLSL HWVNDLPRAF
KQIHYVLKPD GVFIGAMFGG DTLFELRCSL QLAELEREGG FSPHISPFTA VNDLGHLLGR
AGFNTLTVDT DEIQVNFPGM FEVMEDLQGM GESNCSWNRK PLLHRETMLA AAAIYQEMYG
NEDGSVPATF QIYYMIGWKY HDSQARPAQR GSATVSFGDL GKINNLISHG KK
//
