ID G3WTV9_SARHA Unreviewed; 514 AA.
AC G3WTV9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Syntaxin binding protein 4 {ECO:0000313|Ensembl:ENSSHAP00000018864.2};
GN Name=STXBP4 {ECO:0000313|Ensembl:ENSSHAP00000018864.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000018864.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000018864.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000018864.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3WTV9; -.
DR STRING; 9305.ENSSHAP00000018864; -.
DR Ensembl; ENSSHAT00000019020.2; ENSSHAP00000018864.2; ENSSHAG00000016013.2.
DR eggNOG; KOG3528; Eukaryota.
DR GeneTree; ENSGT00390000002226; -.
DR HOGENOM; CLU_022133_1_0_1; -.
DR OrthoDB; 2914766at2759; -.
DR TreeFam; TF331084; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR PANTHER; PTHR19964:SF16; SYNTAXIN-BINDING PROTEIN 4; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648}.
FT DOMAIN 23..97
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 177..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 313..410
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 183..200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 514 AA; 57753 MW; D6CFE7D94D030282 CRC64;
MMTGMNGNNS ETTAFNQVAM DPAFQMITVT KAIGLGLNIV GGINRNEGPL VYIQEIIAGG
DCHKDGRLKP GDQLVYINKE SLIGVSFEEA KSIITRAKLR SESAWEIGFI RQKLSSNQQE
TTQRSSLLSS TEGCETQVST SFNVLSHHEN FDQKMSSTPI TVDTTLMSLK KNQIKTGFKK
REPSPITSPN NSPTDVSNPN INPNWPNDTG LQGENISLDP SIRLKIEKLE MALNYLGIQP
TEEEHKALRQ QVQIDSKGTV SFGDFVQVSR ELFRLQLNEV TIGQKSTMLS AREISHLLES
QLLPHDSSEM DEVEKLKHER NDALREVSKL KDKLLESENQ RKQLTEELQN VKQEAKAVVE
ETRALRSRLH LAEAAQRQAH GMEMDYEEVI RLLEAEIKEL KAQLADHTGQ SKESFQDLRK
RITVLDCQLR KSETARKTFE LTTEKLLNFV ETIQEVLSDH SSSLSNFSDR RSILGSQTLF
PQLGRNGRNV TANLVQESRE LAKSVRALLD VDPS
//
