ID G3XNA8_ASPNA Unreviewed; 997 AA.
AC G3XNA8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Histone deacetylase domain-containing protein {ECO:0000259|Pfam:PF00850};
DE Flags: Fragment;
GN ORFNames=ASPNIDRAFT_201349 {ECO:0000313|EMBL:EHA27565.1};
OS Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 /
OS NCTC 3858a / NRRL 328 / USDA 3528.7).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=380704 {ECO:0000313|EMBL:EHA27565.1, ECO:0000313|Proteomes:UP000009038};
RN [1] {ECO:0000313|EMBL:EHA27565.1, ECO:0000313|Proteomes:UP000009038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a /
RC NRRL 328 / USDA 3528.7 {ECO:0000313|Proteomes:UP000009038};
RX PubMed=21543515; DOI=10.1101/gr.112169.110;
RA Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.,
RA Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., Albermann K.,
RA Berka R.M., Braus G.H., Braus-Stromeyer S.A., Corrochano L.M., Dai Z.,
RA van Dijck P.W., Hofmann G., Lasure L.L., Magnuson J.K., Menke H.,
RA Meijer M., Meijer S.L., Nielsen J.B., Nielsen M.L., van Ooyen A.J.,
RA Pel H.J., Poulsen L., Samson R.A., Stam H., Tsang A., van den Brink J.M.,
RA Atkins A., Aerts A., Shapiro H., Pangilinan J., Salamov A., Lou Y.,
RA Lindquist E., Lucas S., Grimwood J., Grigoriev I.V., Kubicek C.P.,
RA Martinez D., van Peij N.N., Roubos J.A., Nielsen J., Baker S.E.;
RT "Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015
RT versus enzyme-producing CBS 513.88.";
RL Genome Res. 21:885-897(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA27565.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACJE01000002; EHA27565.1; -; Genomic_DNA.
DR AlphaFoldDB; G3XNA8; -.
DR STRING; 380704.G3XNA8; -.
DR HOGENOM; CLU_001880_0_1_1; -.
DR Proteomes; UP000009038; Unassembled WGS sequence.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd09998; HDAC_Hos3; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR47558; HISTONE DEACETYLASE HOS3; 1.
DR PANTHER; PTHR47558:SF1; HISTONE DEACETYLASE HOS3; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
FT DOMAIN 268..600
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 1..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 672..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 782..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..880
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 918..957
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 958..990
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 997
FT /evidence="ECO:0000313|EMBL:EHA27565.1"
SQ SEQUENCE 997 AA; 106447 MW; 8805FACD326EFF9D CRC64;
MDPSKRHEPT SFTAASSPPA TGPPLSTDDA TSSTHRLSHP SLHAMSLPPS SPGLSSAALL
SPSDPPARAV ATQAHPTPRR IPSSSSLAEE RRKSSPSLKK RSSTASLRSN RGASTSPRPS
LSRHSSSSFG TSPTSASATH PNMAKKAHRT VSAEHPVTTA ASIAAESFRK EVDWHQSAKL
QSQTLVLVHD ACYGHRFSRP RTSRAALNSI VERPERIQAS VLGISAAYVR LARRHAGGAF
APHPDLNPQQ LPVPPFHIRK TARTLSLSSP AVTHVHGSKW MEDLKTMCDA AESRLALNGK
ELVRPRSAGK DSAATNAPAF HEGDLYLCSE SLSAFEGALG GVSEGVDAVM GPAPTKRAFV
CIRPPGHHCS AGHPSGFCWI NNVHVGISYA AMTHGLTHAA ILDFDLHHGD GSQDIAWQQN
HRAVTAPRNA AAHRKTMVGY FSLHDINSYP CEMGEPEKVR NASVCIDKAH GQSIWNVHLE
PWKSNKEFWD LYAAKYTVLI DKARAFLRMH TERLANTPNG PPPKAAIFIS AGFDASEWEG
AGMQRHQVNV PTEFYARFTA DVVRMANEEG LGTDGRIISV LEGGYSNRAL TSGVLSHLSG
LGDAKGSTHD VDEQQINRLA SEMTDRLGLS NSAEGRSVTE PVYNSEWWSP GVLEELEALV
YSPAAPVKPR EKAAPTYLTT TQSFSAKVVN PPRDRRSTGS HSSPEPEAPS PPPPVSWATA
THELCKVLIP TGRQTTSCQP EELNAEASRL RRERQTAVDA ASTSATTAAV AAAAAAAATA
TATAAEDSRM KLRVRKPKPS LPLSPSAETV KRPAARGSRR TTIDTAPDTA PAVQTPARVT
RRKSAGAGSA ASTPEPTGPR PATSATVRKT NTSQSSTPRL PSSPNTPPVP RVPPAFLSAE
SEESPNPDGP QDDLDSLTAG VRKLHIKLKV PSPEENAARE RERERRIAEE RKRTASKATS
KTQTQTQTPK SPRKPAGRAQ TSSASKTASR SAAKPAP
//
