ID G3XPW4_ASPNA Unreviewed; 2245 AA.
AC G3XPW4;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 03-MAY-2023, entry version 54.
DE RecName: Full=Dynamin-binding protein {ECO:0000256|ARBA:ARBA00018186};
DE AltName: Full=Scaffold protein Tuba {ECO:0000256|ARBA:ARBA00032587};
GN ORFNames=ASPNIDRAFT_128721 {ECO:0000313|EMBL:EHA27313.1};
OS Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 /
OS NCTC 3858a / NRRL 328 / USDA 3528.7).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=380704 {ECO:0000313|EMBL:EHA27313.1, ECO:0000313|Proteomes:UP000009038};
RN [1] {ECO:0000313|EMBL:EHA27313.1, ECO:0000313|Proteomes:UP000009038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a /
RC NRRL 328 / USDA 3528.7 {ECO:0000313|Proteomes:UP000009038};
RX PubMed=21543515; DOI=10.1101/gr.112169.110;
RA Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.,
RA Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., Albermann K.,
RA Berka R.M., Braus G.H., Braus-Stromeyer S.A., Corrochano L.M., Dai Z.,
RA van Dijck P.W., Hofmann G., Lasure L.L., Magnuson J.K., Menke H.,
RA Meijer M., Meijer S.L., Nielsen J.B., Nielsen M.L., van Ooyen A.J.,
RA Pel H.J., Poulsen L., Samson R.A., Stam H., Tsang A., van den Brink J.M.,
RA Atkins A., Aerts A., Shapiro H., Pangilinan J., Salamov A., Lou Y.,
RA Lindquist E., Lucas S., Grimwood J., Grigoriev I.V., Kubicek C.P.,
RA Martinez D., van Peij N.N., Roubos J.A., Nielsen J., Baker S.E.;
RT "Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015
RT versus enzyme-producing CBS 513.88.";
RL Genome Res. 21:885-897(2011).
CC -!- SUBCELLULAR LOCATION: Cell junction {ECO:0000256|ARBA:ARBA00004282}.
CC Golgi apparatus, Golgi stack {ECO:0000256|ARBA:ARBA00004348}.
CC -!- SIMILARITY: Belongs to the peptidase C48 family.
CC {ECO:0000256|ARBA:ARBA00005234}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA27313.1}.
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DR EMBL; ACJE01000003; EHA27313.1; -; Genomic_DNA.
DR STRING; 380704.G3XPW4; -.
DR HOGENOM; CLU_001112_0_0_1; -.
DR Proteomes; UP000009038; Unassembled WGS sequence.
DR GO; GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.
DR GO; GO:0008234; F:cysteine-type peptidase activity; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0019783; F:ubiquitin-like protein peptidase activity; IEA:UniProt.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd07589; BAR_DNMBP; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR003653; Peptidase_C48_C.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF20; NUCLEAR FUSION PROTEIN FUS2; 1.
DR Pfam; PF02902; Peptidase_C48; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50600; ULP_PROTEASE; 1.
PE 3: Inferred from homology;
KW Cell junction {ECO:0000256|ARBA:ARBA00022949}.
FT DOMAIN 1191..1413
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 1448..1665
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 2019..2188
FT /note="Ubiquitin-like protease family profile"
FT /evidence="ECO:0000259|PROSITE:PS50600"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 56..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 243..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 721..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 770..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 879..909
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 951..985
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1035..1066
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1078..1117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1133..1192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1271..1292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1702..1802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1817..1864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..619
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 626..641
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..745
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 879..904
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1035..1063
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1078..1092
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1101..1117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1135..1182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1702..1757
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1773..1802
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2245 AA; 248506 MW; 1EFE7AE6763B83C1 CRC64;
MSEGDVEHVS GLFDGSPRQF QRLSSQSTTD YFYDALSNGA REDHLAALSS TPVPLSGKAY
PTQPGLTNLQ PFPPPTSIPP EGHPNSYDRS SPDPDDYYRP HLPTVAANDE EDLDLSAGHP
MLEVGSDAAA DNRPKPFQRV SSVPIHLLES TSAGLSQYRS ASDSSYKSVG HEPTWGSSVR
ASAARSGQTS FKDLINKFNN NVDQVLPVPS TSTVRSRVTS RAASPTSPTQ SSQSRALPRL
RETHHLSSRP QSGHWQPRSV FDTESPSDLL AASLTTAGVD DNHSSTLASS DAIPRRPTLG
EPLRIDTSPQ ISGYGNSSRI RRRGSDGIIP SPNPAFLDPF DPSAGVTPLT PTAWYLGRTP
FLESVSTGSN TNPHRRTKSD IPGNWSIEVA ASPPDSHMAV PAPLQANSQA CPDNSPHTPK
SRIPISSHRL NSPSVSDESP PPSRAGTHSG NRATVQVHLP PKGTSRLPKP SPKSPRDMPK
NDQLPGYAAS PRAKREMAHS RSRQQLPERN ALLEAYIAAP PPKKSPPLRS SRPRQPIAHT
QSSRSKVVET VSNFQRQINR DREYRTSRAR ERRLPELGHV DFATRRQKIQ QAFNRTVEEN
ERKEEKAAEL RRQTKAQEDK PELAQASTAE PSQPTESEVQ PSLHADDNET VIEETVAAPI
EESNQVPETK DPRPRPELHV DTDVHTTLEN VDGASDTHLM TMDSPTLGHA AIIERDLAYE
PKSHGPPASD VTSESNETHV TAFDTEPQVE LSRKDLHTSH RTLLSQIMNI RESSPSSSSC
DEQECSFSDN DERDPLPTRL RNAFAFDDQA DSSDNPESCD IYMRHGVMNG ETSNRWSMSS
WSSSLRNQHS ADEQCDNSGD DFSHLQQCTE DSEVATQSCS ASSSTPSITD HKLLSSSSPK
NGNAKEGRQE AVAHPNGFAF SNASSLARLG GWDSKRVGQL YLQELANGRG HGLPLPAIRA
SPEPSQTYAD KETDQGSEGL TDDPVVVSRL RDPPALERPG HTASLVLRDD WEHASPSIMD
WMQVAAAEDE SVLQAQNGNT GPVPDSATTP RLVTPNPQSS CSEEADEGLG LAIKVHQPQE
LDSREKQLPS VPEPPEEDIP TQNIAPQQRT QPPSNVNATE QRLSTIISGI FAPLDPVQST
GSSEDSSLRR LDPIPSPQTF DSSSTSLVPS TSEPSRLKAQ SPSPEQRRLK KRRHVIKELV
DTEYTFGRDM KVVDDIYKGT SSSCLDLSSE DVKILFANSD QVVQFSMAFQ DALKEAAKSV
YVMPKSQRWS SKRSARHHAS RTDSENSSTA GISDLDKDRM TYIGQAFMNQ MGYMEKVYAD
YLKNHDAANK KLQTLQRNPK VAIWLKECRD WASDLTTAWD LDSLLVKPVQ RILKYPLLLA
ELLDSTPDDH PDHPALVSAL EEVTNISVRI NEMKKRADLV GQVVGRKRKE SDVRAGLSKA
FGRRTEKLKQ QVGLSDMVED KEYDTLAQKF GDNFFQLQLV MRDAEMYTRE VQTSMDGFNE
FVEAIQGFVN VSPSNYAELE GRWRELKTTV AEIMTVALPE HIAVVRKSVI DPMVTLLKLH
DGPQRVMRKR DKRLMDYARF KAAKERGDKP DKKTTEQGEQ FVALNETLKD ELPKLYALTA
KLMEACLKNF VHIQTTWFRQ LQHKLGSLFE AFPEDIQKIV EDWSCNFNFS ESQVLSLGIC
NGSLLADTVN LVNFNTPSTG ATINSPRRPS TVNSVSTRVG STMEDSPKVS QEFGNGSHSF
HSPSFETQSQ VSHGRHRADS TFSGRTGHET AEIPRSQMLQ QITSTSTASV PASTSTTEAF
PSLPRLSLDS PFLVDVIGPS SDGNGGAKVE EPPTSPDGRY SGFFSSAMPM SDNPQENAPA
HSERPHEPAV LFLAASIYEF NIDRARREAG YPYLTYVVGE IFDVIAEKGE LWLAKNQDDP
THQWLRMADD RRPTTNLQLR SSAIVSISPR FVNCWSLHHH LPYSPSFPSQ LAPDVLPYVI
RAPQPGITNT NIPCLGVLNT MRDGGLGKLQ RRMRRFGDTL NPDDAYLSLT RGDMQSLKND
WLTDNVISFW EEYLEHEFLV QYRSSNIVLL RPSMSFMILQ TPNPHSLREA LPDFSRTTHV
FLPINDCRNV TEAEGGTHWS LLLISIVDGI AFHYDSLPPG NFWEARTVTM KFAALLGRPI
NYVHLEDSPV QENGSDCGVF VCLSMRHLLL KRLLTANANE KVSMSLGGRK VDARSGRKEM
AKIIEGFRKE GERRRSYVIE PPANN
//
