ID G4HB19_9BACL Unreviewed; 587 AA.
AC G4HB19;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:EHB67128.1};
DE EC=3.2.1.23 {ECO:0000313|EMBL:EHB67128.1};
GN ORFNames=PaelaDRAFT_1352 {ECO:0000313|EMBL:EHB67128.1};
OS Paenibacillus lactis 154.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=743719 {ECO:0000313|EMBL:EHB67128.1, ECO:0000313|Proteomes:UP000003891};
RN [1] {ECO:0000313|EMBL:EHB67128.1, ECO:0000313|Proteomes:UP000003891}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=154 {ECO:0000313|EMBL:EHB67128.1,
RC ECO:0000313|Proteomes:UP000003891};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Siebers A., Thelen M., Hugenholtz P.,
RA Allgaier M., Woyke T.J.;
RT "The draft genome of Paenibacillus lactis 154.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809}.
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DR EMBL; AGIP01000002; EHB67128.1; -; Genomic_DNA.
DR RefSeq; WP_007128527.1; NZ_AGIP01000002.1.
DR AlphaFoldDB; G4HB19; -.
DR STRING; 743719.PaelaDRAFT_1352; -.
DR PATRIC; fig|743719.3.peg.1357; -.
DR eggNOG; COG1874; Bacteria.
DR OrthoDB; 9813184at2; -.
DR Proteomes; UP000003891; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR026283; B-gal_1-like.
DR InterPro; IPR048912; BetaGal1-like_ABD1.
DR InterPro; IPR048913; BetaGal_gal-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR019801; Glyco_hydro_35_CS.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF165; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF21317; BetaGal_ABD_1; 1.
DR Pfam; PF21467; BetaGal_gal-bd; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PIRSF; PIRSF006336; B-gal; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01182; GLYCOSYL_HYDROL_F35; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:EHB67128.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EHB67128.1}.
FT DOMAIN 10..324
FT /note="Glycoside hydrolase 35 catalytic"
FT /evidence="ECO:0000259|Pfam:PF01301"
FT DOMAIN 372..481
FT /note="Beta-galactosidase 1-like first all-beta"
FT /evidence="ECO:0000259|Pfam:PF21317"
FT DOMAIN 505..563
FT /note="Beta-galactosidase galactose-binding"
FT /evidence="ECO:0000259|Pfam:PF21467"
FT ACT_SITE 158
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
FT ACT_SITE 234
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR006336-1"
SQ SEQUENCE 587 AA; 66009 MW; 910FE3DF5A0B3B80 CRC64;
MTQLKAVNQQ FVLGEEAIQI LSGAIHYFRV VPEYWEDRLL KLKACGLNTV ETYIPWNWHE
PDEGRFNFSG MADIEAFITL AGKLGLHVIV RPSPYICAEW EFGGLPAWLL QDPHMQLRCL
DPKFLKKVDA YYDELIPRLV PLLSTNGGPI IAVQIENEYG SYGNDTAYLQ YLQEALIARG
VDVLLFTSDG PTDGMLQGGT VPGVTATVNF GSRPSEAFAK LREYRSEDPL MCMEYWNGWF
DHWMKPHHTR DSEDAASVFA EMLALGASVN FYMFHGGTNF GFYNGANYHD KYEPTITSYD
YDAPLSECGD VTTKYEAVRQ VIAKHQGVEL GDLPALPDPV RKKAYGTVSM TSYADLLENL
PVLASSEKHR TPVPMELLGQ NYGFIVYSTK ISGPRQGESL HLQEVHDRAQ VFLDGVYQGT
VERWNNAPIS LDIPAAGAKL DIVVENMGRV NYGPRLKDYK GITEGVRMNN QFLYDWSISC
LPMDHLEAVP FGPLPAPNAG RKDRPAFYKG EFHVEDRMDT FVRLDGWVKG VVWINGFNLG
RYWEQGPQAT LYLPGPLLKK GSNEIIVFEL HHTDKASIEL VDKPDLG
//
