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Database: UniProt
Entry: G4KPV6_OSCVS
LinkDB: G4KPV6_OSCVS
Original site: G4KPV6_OSCVS 
ID   G4KPV6_OSCVS            Unreviewed;       437 AA.
AC   G4KPV6;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   05-JUL-2017, entry version 45.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:BAK97199.1};
GN   OrderedLocusNames=OBV_00010 {ECO:0000313|EMBL:BAK97199.1};
OS   Oscillibacter valericigenes (strain DSM 18026 / NBRC 101213 /
OS   Sjm18-20).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Oscillospiraceae;
OC   Oscillibacter.
OX   NCBI_TaxID=693746 {ECO:0000313|EMBL:BAK97199.1, ECO:0000313|Proteomes:UP000005219};
RN   [1] {ECO:0000313|Proteomes:UP000005219}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18026 / NBRC 101213 / Sjm18-20
RC   {ECO:0000313|Proteomes:UP000005219};
RA   Katano Y., Fujinami S., Kawakoshi A., Ohji S., Nakazawa H., Ankai A.,
RA   Oguchi A., Fukui S., Terui Y., Harada T., Takahashi M., Suzuki K.,
RA   Fujita N.;
RT   "Whole genome sequence of Oscillibacter valericigenes Sjm18-20.";
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; AP012044; BAK97199.1; -; Genomic_DNA.
DR   RefSeq; WP_014115901.1; NC_016048.1.
DR   STRING; 693746.OBV_00010; -.
DR   EnsemblBacteria; BAK97199; BAK97199; OBV_00010.
DR   KEGG; ova:OBV_00010; -.
DR   PATRIC; fig|693746.9.peg.1; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000005219; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005219};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005219}.
FT   DOMAIN      132    260       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      343    412       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     140    147       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   437 AA;  49583 MW;  A8A09B0AF20418F4 CRC64;
     MNSVADVWTN VLTQLKRDLS ETTIATWFDE LEAVDLRDGV FYLHCPNDFK KNYIESLFMK
     NIKAVLHDIF STDFEVKVLS TEEYAEFSGG AQKKKSEAFT SDEFTFETFV VGPSNKLAYA
     ASVSVAEHPA KNYNPLLIYG DSGLGKTHLI YSIAHVIQKN DHNAKIAYVK GDDLTNELVN
     AIREGKTAEM REKYRKADLL LVDDVQFIAG RKQTQEEFFH TFNNLYESGK QIVLTSDRPP
     SEMMQLEDRL RTRFEWGLLV DVAPPDYETR LAIIKNKAAL LGMEIPNKVA VYIAEHVTSN
     VRQLEGTINK LLAYKDLLGD DVDEELVKRA IQDILRRGDN IPTPDSIVEF VSKYYGVDAE
     VIRGQQRVRE AVAARQVAMY LIRSMTNLSS DDIGKFFGNR DHSTVLYSIE KVEKQMKSNA
     AYSETVKEIK TNISSSH
//
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