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Database: UniProt
Entry: G4L360_TETHN
LinkDB: G4L360_TETHN
Original site: G4L360_TETHN 
ID   G4L360_TETHN            Unreviewed;       444 AA.
AC   G4L360;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   05-JUL-2017, entry version 44.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:BAK93327.1};
GN   OrderedLocusNames=TEH_00010 {ECO:0000313|EMBL:BAK93327.1};
OS   Tetragenococcus halophilus (strain DSM 20338 / JCM 20259 / NCIMB 9735
OS   / NBRC 12172) (Pediococcus halophilus).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Tetragenococcus.
OX   NCBI_TaxID=945021 {ECO:0000313|EMBL:BAK93327.1, ECO:0000313|Proteomes:UP000002663};
RN   [1] {ECO:0000313|EMBL:BAK93327.1, ECO:0000313|Proteomes:UP000002663}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 20338 / JCM 20259 / NCIMB 9735 / NBRC 12172
RC   {ECO:0000313|Proteomes:UP000002663};
RA   Nakazawa H., Omata S., Koga C., Watanabe Y., Katano Y., Ito N.,
RA   Tsukatani N., Ankai A., Oguchi A., Fukui S., Yashiro I., Kamata S.,
RA   Hashimoto Y., Yamazaki J., Taguchi H., Tanaka A., Koyama T.,
RA   Ichige A., Hanya Y., Tanikawa S., Yamazaki S., Fujita N.;
RT   "Whole genome sequence of Tetragenococcus halophilus NBRC 12172.";
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; AP012046; BAK93327.1; -; Genomic_DNA.
DR   RefSeq; WP_014123398.1; NC_016052.1.
DR   STRING; 945021.TEH_00010; -.
DR   EnsemblBacteria; BAK93327; BAK93327; TEH_00010.
DR   KEGG; thl:TEH_00010; -.
DR   PATRIC; fig|945021.8.peg.1; -.
DR   eggNOG; ENOG4105CI4; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OMA; REFNPLF; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000002663; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002663};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002663}.
FT   DOMAIN      140    271       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      352    421       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     148    155       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   444 AA;  50753 MW;  3EF8A990660A25E0 CRC64;
     MPSLETIWKE LQDSYRKEMN PVSYNTWIEP AKPISYYDNQ LIIEVPTTVQ KNYWEKNLAG
     KILETFFMMS GEEILPTFVT PDEAERYKQK EVEPEEETPK VPEHKTMLNS KYTFDTFVIG
     KGNQMAHAAA LVVAEEPASI YNPLFFYGGV GLGKTHLMQA IGHQMLVTHP NAKIKYVSSE
     NFTNDFISSI QNNKMEEFRN EYRTMDLLLV DDIQFLVNKE GTQEEFFNTF EELYRNNKQI
     VLTSDRLPNE IPTLPQRLVS RFAWGLSVDI TPPDLETRTA ILRKKAEAEN LEIPDDALSY
     IAGQIDSNIR ELEGALVRVQ AYAAIQSSDI TTSLAAEALK ALKIGTNLSQ LTVEQVQEEV
     ADYYHLNVSD LTGKKRTKSI VVPRQIAMYL CRELTDYSLP KIGADFGGKD HTTVIHAYEK
     VQKLMEEDEK AQSEIKEIKN HLMQ
//
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