ID G4SZ11_META2 Unreviewed; 456 AA.
AC G4SZ11;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=AMP nucleosidase {ECO:0000256|ARBA:ARBA00011985};
DE EC=3.2.2.4 {ECO:0000256|ARBA:ARBA00011985};
DE AltName: Full=AMP nucleosidase {ECO:0000256|ARBA:ARBA00031983};
GN OrderedLocusNames=MEALZ_3812 {ECO:0000313|EMBL:CCE25468.1};
OS Methylotuvimicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM
OS B-2133 / 20Z) (Methylomicrobium alcaliphilum).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylotuvimicrobium.
OX NCBI_TaxID=1091494 {ECO:0000313|EMBL:CCE25468.1, ECO:0000313|Proteomes:UP000008315};
RN [1] {ECO:0000313|Proteomes:UP000008315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z
RC {ECO:0000313|Proteomes:UP000008315};
RX PubMed=22207753; DOI=10.1128/JB.06392-11;
RA Vuilleumier S., Khmelenina V.N., Bringel F., Reshetnikov A.S., Lajus A.,
RA Mangenot S., Rouy Z., Op den Camp H.J., Jetten M.S., Dispirito A.A.,
RA Dunfield P., Klotz M.G., Semrau J.D., Stein L.Y., Barbe V., Medigue C.,
RA Trotsenko Y.A., Kalyuzhnaya M.G.;
RT "Genome sequence of the haloalkaliphilic methanotrophic bacterium
RT Methylomicrobium alcaliphilum 20Z.";
RL J. Bacteriol. 194:551-552(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=AMP + H2O = adenine + D-ribose 5-phosphate;
CC Xref=Rhea:RHEA:20129, ChEBI:CHEBI:15377, ChEBI:CHEBI:16708,
CC ChEBI:CHEBI:78346, ChEBI:CHEBI:456215; EC=3.2.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000274};
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DR EMBL; FO082060; CCE25468.1; -; Genomic_DNA.
DR RefSeq; WP_014150221.1; NC_016112.1.
DR AlphaFoldDB; G4SZ11; -.
DR STRING; 1091494.MEALZ_3812; -.
DR KEGG; mah:MEALZ_3812; -.
DR PATRIC; fig|271065.3.peg.3940; -.
DR HOGENOM; CLU_047550_0_0_6; -.
DR Proteomes; UP000008315; Chromosome.
DR GO; GO:0008714; F:AMP nucleosidase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.450; -; 1.
DR Gene3D; 3.30.1850.10; MoCo carrier protein-like; 1.
DR InterPro; IPR031100; LOG_fam.
DR InterPro; IPR049788; PpnN.
DR InterPro; IPR037153; PpnN-like_sf.
DR InterPro; IPR021826; PpnN_C.
DR InterPro; IPR027820; PpnN_N.
DR NCBIfam; NF038390; Nsidase_PpnN; 1.
DR PANTHER; PTHR43393; CYTOKININ RIBOSIDE 5'-MONOPHOSPHATE PHOSPHORIBOHYDROLASE; 1.
DR PANTHER; PTHR43393:SF1; PYRIMIDINE_PURINE NUCLEOTIDE 5'-MONOPHOSPHATE NUCLEOSIDASE; 1.
DR Pfam; PF14793; DUF4478; 1.
DR Pfam; PF03641; Lysine_decarbox; 1.
DR Pfam; PF11892; PpnN_C; 1.
DR SUPFAM; SSF102405; MCP/YpsA-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008315}.
FT DOMAIN 9..116
FT /note="Pyrimidine/purine nucleotide 5'-monophosphate
FT nucleosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14793"
FT DOMAIN 335..455
FT /note="Pyrimidine/purine nucleotide 5'-monophosphate
FT nucleosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11892"
SQ SEQUENCE 456 AA; 50782 MW; F376AD4072A2886D CRC64;
MKQDVVDARI SPAGHLAVLS KTEVNKLLDT SQGGLYRLLH NCSLAVLNCG NYMDDGKELL
ERYKSFEIRV LQEERGIKLE VKGAPATAFV DGHMIKGIKE HLFAVLRDII YVSDEINDNP
KFDLQSSDGV TNSVFHILRN ANILKAGKLP QLVVCWGGHS ISREEYDYSK VVGYQMGLRG
LDICTGCGPG AMKGPMKGAT IGHAKQRIGT GHYIGITEPG IIAAEAPNPI VNDLVIMPDI
EKRLEAFVRA GHGIVVFPGG VGTAEEILYL LGILLHPDNK DIPFPLIFTG PAGSEEYYKQ
INRFIGDTLG LAAQQRYKII IDDPARVARD MKEGMQRVRE FRQQREDAYY FNWALQISPE
FQQPFNPTHK NMAALQLHKD QESHHLAANL RRVFSGIVSG NVKDDGIRAI EQHGHFEIKG
DAEIMGPVDE LLSAFVKQQR MKLPGKTYKP CYRIVK
//
