ID G4T2T4_META2 Unreviewed; 326 AA.
AC G4T2T4;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Zinc-binding dehydrogenase superfamily (Quinone oxidoreductase, NADPH dependent) {ECO:0000313|EMBL:CCE22568.1};
DE EC=1.6.5.5 {ECO:0000313|EMBL:CCE22568.1};
GN OrderedLocusNames=MEALZ_0874 {ECO:0000313|EMBL:CCE22568.1};
OS Methylotuvimicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM
OS B-2133 / 20Z) (Methylomicrobium alcaliphilum).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methylotuvimicrobium.
OX NCBI_TaxID=1091494 {ECO:0000313|EMBL:CCE22568.1, ECO:0000313|Proteomes:UP000008315};
RN [1] {ECO:0000313|Proteomes:UP000008315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z
RC {ECO:0000313|Proteomes:UP000008315};
RX PubMed=22207753; DOI=10.1128/JB.06392-11;
RA Vuilleumier S., Khmelenina V.N., Bringel F., Reshetnikov A.S., Lajus A.,
RA Mangenot S., Rouy Z., Op den Camp H.J., Jetten M.S., Dispirito A.A.,
RA Dunfield P., Klotz M.G., Semrau J.D., Stein L.Y., Barbe V., Medigue C.,
RA Trotsenko Y.A., Kalyuzhnaya M.G.;
RT "Genome sequence of the haloalkaliphilic methanotrophic bacterium
RT Methylomicrobium alcaliphilum 20Z.";
RL J. Bacteriol. 194:551-552(2012).
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DR EMBL; FO082060; CCE22568.1; -; Genomic_DNA.
DR AlphaFoldDB; G4T2T4; -.
DR STRING; 1091494.MEALZ_0874; -.
DR KEGG; mah:MEALZ_0874; -.
DR PATRIC; fig|271065.3.peg.891; -.
DR HOGENOM; CLU_026673_3_4_6; -.
DR Proteomes; UP000008315; Chromosome.
DR GO; GO:0003960; F:NADPH:quinone reductase activity; IEA:UniProtKB-EC.
DR CDD; cd05276; p53_inducible_oxidoreductase; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR014189; Quinone_OxRdtase_PIG3.
DR NCBIfam; TIGR02824; quinone_pig3; 1.
DR PANTHER; PTHR48106:SF8; QUINONE OXIDOREDUCTASE PIG3; 1.
DR PANTHER; PTHR48106; QUINONE OXIDOREDUCTASE PIG3-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:CCE22568.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008315}.
FT DOMAIN 14..324
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 326 AA; 34547 MW; 55DCF347E0C699CC CRC64;
MPQDMQAIEI VAPGKLGTTH RPLPMPLADE VLIRVEAAGV NRPDIMQRQG LYPPPPGASD
IPGLEVAGTI AVLGGDVRHL QLGDRVCALV TGGGYAQYCT AAAELCLPIP KGITVIQAAG
LPETFFTVWS NLFDRAGLKP GETLLVHGGS SGIGVTAIQM AKAFGVRVFV TAGSARKSAF
CLELGADAAI NYREQDFVEE VSALTSGRGV DVILDMIGGD YFPRNLKCMA FDARLVQIAV
QGGPKAEINL LQVFLKRLTI TGSTLRARDN AFKSAIAGKL REHVWPLLES GDIHPVIDTV
LPLAEAAEAH ALMESSQHIG KIILTV
//
