ID   G4T4P0_META2            Unreviewed;       781 AA.
AC   G4T4P0;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=Peptidase S8/S53 domain-containing protein {ECO:0000259|Pfam:PF00082};
GN   OrderedLocusNames=MEALZ_p0091 {ECO:0000313|EMBL:CCE25796.1};
OS   Methylotuvimicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM
OS   B-2133 / 20Z) (Methylomicrobium alcaliphilum).
OG   Plasmid MEALZ_p {ECO:0000313|EMBL:CCE25796.1,
OG   ECO:0000313|Proteomes:UP000008315}.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC   Methylococcaceae; Methylotuvimicrobium.
OX   NCBI_TaxID=1091494 {ECO:0000313|EMBL:CCE25796.1, ECO:0000313|Proteomes:UP000008315};
RN   [1] {ECO:0000313|EMBL:CCE25796.1, ECO:0000313|Proteomes:UP000008315}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z
RC   {ECO:0000313|Proteomes:UP000008315};
RX   PubMed=22207753; DOI=10.1128/JB.06392-11;
RA   Vuilleumier S., Khmelenina V.N., Bringel F., Reshetnikov A.S., Lajus A.,
RA   Mangenot S., Rouy Z., Op den Camp H.J., Jetten M.S., Dispirito A.A.,
RA   Dunfield P., Klotz M.G., Semrau J.D., Stein L.Y., Barbe V., Medigue C.,
RA   Trotsenko Y.A., Kalyuzhnaya M.G.;
RT   "Genome sequence of the haloalkaliphilic methanotrophic bacterium
RT   Methylomicrobium alcaliphilum 20Z.";
RL   J. Bacteriol. 194:551-552(2012).
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073}.
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DR   EMBL; FO082061; CCE25796.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4T4P0; -.
DR   KEGG; mah:MEALZ_p0091; -.
DR   HOGENOM; CLU_018676_1_0_6; -.
DR   Proteomes; UP000008315; Plasmid MEALZ_p.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd04847; Peptidases_S8_Subtilisin_like_2; 1.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR034074; Y4bN_pept_dom.
DR   PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR   PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
PE   3: Inferred from homology;
KW   Plasmid {ECO:0000313|EMBL:CCE25796.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008315}.
FT   DOMAIN          272..571
FT                   /note="Peptidase S8/S53"
FT                   /evidence="ECO:0000259|Pfam:PF00082"
SQ   SEQUENCE   781 AA;  86379 MW;  B6189129A80CA7D6 CRC64;
     MANRSQGDTR HDRLPIKLIM PKQGAERRVT GGGGPPQPFR VVDDQYRHRL VNQITAIQES
     VLLNLKGVKA APVRVKVIAK AAAKSHRPDT LFSHHTCPII GSGGLGELYI KATPSGLAKL
     KASIEENTSD RIVKELSCIE SIEAVTPLLR RKGVSAEDVL RYSPRGKNGF ITRVKLFSFG
     ANEDQTAIAI EFVEACKAKG IQLDQRGYAA QSWIYAAECR SVADVEALSK IISVRSISHM
     PLVRTVRPKS INLESSLPQL PIRGSDDLDI PVVVVVDSGI SDQILPLNSW IVGRDQQVAE
     PYRNTDHGTF VAGLICWGSE LNPTLSGLES SPCGIFDLQV IPNDDPSRGD TLALMESELL
     MSLEAALDEH ANKYKVWNLS LGTDALCSLD EFSELAVELD NLQEKYQVSF VISAGNYVTP
     PLLDFPRTPN QLESGRITSP ADSILSITVG AVSHVDFKNK GPKQHHPSAF SRHGAGPNYI
     IKPDVVHYGG SCSTDGLHIH GIRSITESGI AEDIGTSFST PLVSRTLAQI YHQITPLPSP
     VLARALLTHH ARDPRSGKRV PDGEENYLGF GLPSSAPYSL ECTPHTATLI FEDTLRPGYF
     LEWDDFPYPP SLMRDGRYFG EVWMTLAFAP SRGARWGTEY CETHIDAHLG VYRERTKRDT
     GEIKVEFKGL VPPEHRNPEL LYEAYQVEKL RKWAPVRTYF GDMGETGERG LRWRLKLQLL
     TRHGVEVDEA AFKPQHFSLI ITIADPAGTA PVYDEMAQIV RNRFQAQNLA IRTRTRIRGT
     T
//