ID   G4TTZ8_SERID            Unreviewed;      1142 AA.
AC   G4TTZ8;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   ORFNames=PIIN_08760 {ECO:0000313|EMBL:CCA74791.1};
OS   Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS   (Piriformospora indica).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Sebacinales; Serendipitaceae; Serendipita.
OX   NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA74791.1, ECO:0000313|Proteomes:UP000007148};
RN   [1] {ECO:0000313|EMBL:CCA74791.1, ECO:0000313|Proteomes:UP000007148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA74791.1,
RC   ECO:0000313|Proteomes:UP000007148};
RX   PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA   Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA   Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA   Kogel K.H.;
RT   "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT   the Mutualistic Root Symbiont Piriformospora indica.";
RL   PLoS Pathog. 7:e1002290-e1002290(2011).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCA74791.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAFZ01000355; CCA74791.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4TTZ8; -.
DR   STRING; 1109443.G4TTZ8; -.
DR   eggNOG; KOG0017; Eukaryota.
DR   HOGENOM; CLU_277579_0_0_1; -.
DR   InParanoid; G4TTZ8; -.
DR   OMA; YTIDEHI; -.
DR   OrthoDB; 1657180at2759; -.
DR   Proteomes; UP000007148; Unassembled WGS sequence.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 1.10.340.70; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR041588; Integrase_H2C2.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR34072; ENZYMATIC POLYPROTEIN-RELATED; 1.
DR   Pfam; PF17921; Integrase_H2C2; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF08284; RVP_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007148}.
FT   DOMAIN          424..609
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          180..210
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          871..994
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        184..201
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        875..890
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        925..949
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        951..994
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1142 AA;  129308 MW;  5E09CA389DDCA42D CRC64;
     MTLFPFEEPN DDTLCIRELG VQEWAENELE TKLRHIPERD CSDILEGIRF SVARLPDCPG
     IFQVHDLLLN MSWSFTSMDL FDGEFNLASA YLEFMDSQES FWLPDVECLK AEMSTDYDWT
     ALQSVQCPPE KGLGELTVPI MPHESQEGRE GTASNGYDSS EDDLESEFSW YTAPNTEQEN
     VRVTIIDEPQ RPKKSSKRRE PRTLLQGNAA KTKDLERRVP KTCIIDAFVN GEAAQALVDT
     GSMSDFVSTT LVDQLRLKYE SLAKPLTVQL AVTGSRGKIN ASTTVAFRYG DICEKRRFDV
     MNIDGYDVIL GTPFLYQHKG VIGFNPTRLA FESIEALPIE GKEVATIASL AASVLNNSLE
     EVREMLRKEA ADLCRPAEET PLPPFRAINH RIPLKNESLQ IPYIPSRCPQ AFQEQWARKR
     DTYIRTGRWE YATGHSGVPM LFIPKKPGPN GEKRPRTVFA KQRLNENTIK LSSPLPDIQS
     ILETIAPHRH KSLIDGRDAY EQIRVESKDV HKTLFNTPDG TMISKVMQQG DCNATATYQT
     LMNYVFAPYI GKFMYVYLDD IIIFSDDVES HVEHIRIVLN TLRREKLYLT SPDKLQFFAN
     PLIVLGHVIN GQGIMTDPHK VDRIENWKVP TNAEQVSMLT GMVQYVARDC HAIAIPLAVL
     SKLQRVREWK WGPTQQRAFE EVKRIVSQWQ HNHRHTIDRS ENADPIGVHV DASLTGAGGI
     IWQGKSFQTG RKIAFWSGKF NSAEQNYPTH DRELLGIIHC LPDHEPFEGL LRQKSLNERQ
     KRWLEALSHF DFNIEYIPGE ENYIADALLR VYSNEPKGIV RADSEFVTKP LPEENEHVLE
     KMIRCRMTRS KPLYTGTEVK AVLELHAVTR AQKAKNARLE TSVQARGTDS SDEDTPVKSP
     LARMKPYARV IEAELSPESE EVTSDSSSET DKPQKGSDLP NDEVDKPNAE PEISVTNNPK
     ATIDNEPTTA NAKLNAPSKE PSPNGDSLSP SLNYPEYSPT LTYIVNEGEP GIQLPDCLKG
     RDDEDNFFAP IVKSLAGHKH FILENGLLYL KDDGRRILCV PDIKIGERSV REIFITHAHS
     LLAHLGLKKT LAYLRDNVWW KEIQRDVAEY CQSCSTCASS KSRTTRPFDL LKSLEVPSRP
     WC
//