ID   G4TUD4_SERID            Unreviewed;       846 AA.
AC   G4TUD4;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=Probable to GDP/GTP exchange factor Rom2p {ECO:0000313|EMBL:CCA74927.1};
DE   Flags: Fragment;
GN   ORFNames=PIIN_08897 {ECO:0000313|EMBL:CCA74927.1};
OS   Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS   (Piriformospora indica).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Sebacinales; Serendipitaceae; Serendipita.
OX   NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA74927.1, ECO:0000313|Proteomes:UP000007148};
RN   [1] {ECO:0000313|EMBL:CCA74927.1, ECO:0000313|Proteomes:UP000007148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA74927.1,
RC   ECO:0000313|Proteomes:UP000007148};
RX   PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA   Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA   Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA   Kogel K.H.;
RT   "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT   the Mutualistic Root Symbiont Piriformospora indica.";
RL   PLoS Pathog. 7:e1002290-e1002290(2011).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCA74927.1}.
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DR   EMBL; CAFZ01000374; CCA74927.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4TUD4; -.
DR   STRING; 1109443.G4TUD4; -.
DR   eggNOG; KOG4305; Eukaryota.
DR   HOGENOM; CLU_001251_2_1_1; -.
DR   InParanoid; G4TUD4; -.
DR   OMA; LSHEINY; -.
DR   OrthoDB; 5100844at2759; -.
DR   Proteomes; UP000007148; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR041675; PH_5.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR46572:SF2; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF15405; PH_5; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00036; CNH; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50219; CNH; 1.
DR   PROSITE; PS50010; DH_2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007148}.
FT   DOMAIN          41..228
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   DOMAIN          263..417
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          438..733
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
FT   REGION          330..365
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          739..777
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        748..762
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CCA74927.1"
SQ   SEQUENCE   846 AA;  95456 MW;  19B83FEBA668ABFF CRC64;
     PGEGDPIGLD DEDDAVLETG QLWIHTVPKE VADTLSDAEK KRQEAINEVI YTERDFVRDM
     EYLRDVWVAG IKNSDVIPAE RRDEFISHVF WNILAIIEVN TRLRDALTKR QKQFMVVGEI
     GDIFKDIVPL FEPFVEYGAH QMYGKYEFEK EKSSNPAFAA WVEEIERLPE SRKLELNGYL
     TKPTTRLARY PLLLDAVLKH TPDNSPDKIN IPEVIQMVRN FLTRVNQKTG EAENRFHLHQ
     LQRQLSFRPG EFVDLRLTAP NRQMIYKGSL NRRGGAGDKE DLQVFLFDHA LLMVKQKSKH
     DQYKVYRRPI PLEFLAVSAA DDPSQVVTIR PSTHGRGGGR GMLIRPQHDH TNSAHGGGGN
     TNGHGSPLSL TARAGNNPHG FPITFTHLGW RGYTITLWAS TFISKKKWLE HIQKQQDLMK
     ERSNLFETVP FAQDFAGSNR VNCAAPFRGG RSIVYGTDDG VYFLDLQDAN KPPMKMLALL
     EVTQVDVMES SQLLIVLSER SVLTFPLEAL EARDPTAGLK RGQRIAAHTS FFKVGVCIDK
     SIVCVVKTSP LSTTVKTFEP VDQSIRGKSK PTFKKLLQGG NDTLRLFKEF YIPVECHSLT
     ILRSRLCIGC ARGFQILDLE SLDTQPLVDP SDPSMEFIEK RENLRPLAIF KVENDFLLCY
     EEWAVFVDRH GFRARGEWIA NWEGRPTAFA YHYPYVMAIE PSFIEIWDVN ACTIRQVILG
     DNLRCLFAEP PVLPSVHANP NQVYPNGPYP PRTSSSTRGP PQIGQHPYMH PGHQHELPGS
     HPTLTYGGRP SMHAMPYPGQ PGAYAHTPPP APGYDIGRRL TLIGSDDSMM ILRPVAQSNG
     AAPQRD
//