ID G4U5U7_NEUT9 Unreviewed; 525 AA.
AC G4U5U7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=SH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=NEUTE2DRAFT_101715 {ECO:0000313|EMBL:EGZ78110.1};
OS Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ78110.1, ECO:0000313|Proteomes:UP000008513};
RN [1] {ECO:0000313|EMBL:EGZ78110.1, ECO:0000313|Proteomes:UP000008513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Genetics 189:55-69(2011).
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DR EMBL; GL890999; EGZ78110.1; -; Genomic_DNA.
DR AlphaFoldDB; G4U5U7; -.
DR STRING; 510952.G4U5U7; -.
DR eggNOG; KOG1843; Eukaryota.
DR eggNOG; KOG3771; Eukaryota.
DR HOGENOM; CLU_025518_1_0_1; -.
DR Proteomes; UP000008513; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0051666; P:actin cortical patch localization; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR CDD; cd07599; BAR_Rvs167p; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR046982; BIN3/RVS161-like.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR47174; BRIDGING INTEGRATOR 3; 1.
DR PANTHER; PTHR47174:SF2; SH3 DOMAIN SIGNALLING PROTEIN (AFU_ORTHOLOGUE AFUA_5G07670); 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 7..241
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 466..525
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 278..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 132..159
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 303..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 57096 MW; 04A372C2A1A9F760 CRC64;
MQSVQRQFTK LRSKGPGNNA AVSVLLKEYE DADQLLARLL ENSRAWKDAW SSIVHHQLQF
VVELEGLYDP IVGASDGHGR ESVPTPRLQL ERTYRLKQAF GELKSELAEE IGTIEDRVIR
PAVEARDCIA PIRKTIKKRE NKRLDYERAQ DKVSKLHKKH TRTPKEEASL AKAEVEMAQA
GDEFAIADEH LQSTLPPIIN ASFSLVPSLL AALVLIQNRL LGLYYTTIHG YCMESGFPSP
PPPMSDVVAA WEAAFVPARD DFESVSIVAR GKAAHSPMAL QAPEGPGRRI SAMIPGRNDM
RRVTSPMPST SGAASTYSSG GSQPGRNNLR IPSAGGYPSR APSPAASDRS SYASSPPASS
YSGYSGSQNQ QRRLDYLAPT DFTAAAALGD RGSVDRGTIE NNRPFPRSPS TTTPLINRAH
SPQATRNAGS ANGNGNGNGN DYFALAVAKK RPPPPPPPKR ITSQQQLVEY VVALYAFAGQ
GAGDLAFNEG DKIKIIKKTN TDQDWWVGEL NGRRGNFPAN YCKPV
//
