ID G4U6K7_NEUT9 Unreviewed; 251 AA.
AC G4U6K7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Exoribonuclease phosphorolytic domain-containing protein {ECO:0000259|Pfam:PF01138};
GN ORFNames=NEUTE2DRAFT_100177 {ECO:0000313|EMBL:EGZ77366.1};
OS Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ77366.1, ECO:0000313|Proteomes:UP000008513};
RN [1] {ECO:0000313|EMBL:EGZ77366.1, ECO:0000313|Proteomes:UP000008513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Genetics 189:55-69(2011).
CC -!- SIMILARITY: Belongs to the RNase PH family.
CC {ECO:0000256|ARBA:ARBA00006678}.
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DR EMBL; GL890999; EGZ77366.1; -; Genomic_DNA.
DR AlphaFoldDB; G4U6K7; -.
DR STRING; 510952.G4U6K7; -.
DR eggNOG; KOG1069; Eukaryota.
DR HOGENOM; CLU_063514_2_2_1; -.
DR Proteomes; UP000008513; Unassembled WGS sequence.
DR GO; GO:0000176; C:nuclear exosome (RNase complex); IEA:UniProt.
DR GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd11372; RNase_PH_RRP46; 1.
DR Gene3D; 3.30.230.70; GHMP Kinase, N-terminal domain; 1.
DR InterPro; IPR001247; ExoRNase_PH_dom1.
DR InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR PANTHER; PTHR11953; EXOSOME COMPLEX COMPONENT; 1.
DR PANTHER; PTHR11953:SF1; EXOSOME COMPLEX COMPONENT RRP46; 1.
DR Pfam; PF01138; RNase_PH; 1.
DR SUPFAM; SSF55666; Ribonuclease PH domain 2-like; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW Exosome {ECO:0000256|ARBA:ARBA00022835};
KW Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 8..137
FT /note="Exoribonuclease phosphorolytic"
FT /evidence="ECO:0000259|Pfam:PF01138"
SQ SEQUENCE 251 AA; 27203 MW; ACB63C2A6A35AE93 CRC64;
MATVAPEASL NALPRADGSA RYSYAGYTVT ASVNGPIEAQ RRDEHAYEAH VDVIVRPSAG
VGGTRERHLE FILQSSLSQI ILVKNFPRSV IQIVLQVEST PENAYVNTKL VQASLNLPII
PALFQTAILA LLSAAVPMKA TATSTVVAVV SDDGSKKIVA DPSPKDIREA TSLHVLAFTS
HDELLLSESE GDFTVKEWDG VYENAQKICC QTASKQDGID MVLDDDASSP DMRHFLRSTL
ETKVASDLHW K
//
