ID   G4U6Q6_NEUT9            Unreviewed;      1346 AA.
AC   G4U6Q6;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=Cep57 centrosome microtubule-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=NEUTE2DRAFT_154082 {ECO:0000313|EMBL:EGZ77415.1};
OS   Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ77415.1, ECO:0000313|Proteomes:UP000008513};
RN   [1] {ECO:0000313|EMBL:EGZ77415.1, ECO:0000313|Proteomes:UP000008513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX   PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA   Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA   Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT   "Massive changes in genome architecture accompany the transition to self-
RT   fertility in the filamentous fungus Neurospora tetrasperma.";
RL   Genetics 189:55-69(2011).
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DR   EMBL; GL890999; EGZ77415.1; -; Genomic_DNA.
DR   eggNOG; ENOG502S7ZB; Eukaryota.
DR   HOGENOM; CLU_005779_0_0_1; -.
DR   Proteomes; UP000008513; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   CDD; cd14686; bZIP; 1.
DR   InterPro; IPR024957; Cep57_MT-bd_dom.
DR   InterPro; IPR025925; PPC89_CLD.
DR   PANTHER; PTHR19336:SF9; SPINDLE POLE BODY PROTEIN PPC89; 1.
DR   PANTHER; PTHR19336; UNCHARACTERIZED DUF1167; 1.
DR   Pfam; PF14197; Cep57_CLD_2; 1.
DR   Pfam; PF06657; Cep57_MT_bd; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008513}.
FT   DOMAIN          620..682
FT                   /note="PPC89 centrosome localisation"
FT                   /evidence="ECO:0000259|Pfam:PF14197"
FT   DOMAIN          1227..1303
FT                   /note="Cep57 centrosome microtubule-binding"
FT                   /evidence="ECO:0000259|Pfam:PF06657"
FT   REGION          241..288
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          334..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          387..432
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          591..612
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          839..860
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1041..1147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          927..968
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        242..274
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1046..1070
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1075..1102
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1103..1147
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1346 AA;  151530 MW;  56AC2AC6BE978B62 CRC64;
     MMPHVGHPTT ASKEVREHRW AKIAFHLGNL PWSRTAGLSQ SEVAGNDRNL NLVSLVASVT
     SNGNEVRLLR AVNGAGSELG VHHKEHADRR CPTFKLPYSG CATALSLGSL GTRNFIQSRR
     ISISLPDSAC AQYLGFQLNY QALVPDRCAS FSTRPFPRIP LPLRLLATRR KESATRSSGE
     SLAGVLSLLA PALIPGWLER DTSTDRDWTL ANTTLDAPLR PRKPKHISRL KREMYQLRLK
     NNPFGSPPSS TGDHDTVSTT TEDLSRNLSA FSFNPDDEGT RKASEDYRLP TKRHATRSGR
     FGSRQQREQQ QATMLNTSAI GRAFPEWTGP INDTAPTTQN FDTNMGYNPY PEVKNRKENV
     RPITELTEEH LLNYGLDPKK KTRVEMQPRV ENESDCSTIL SRSPGRGARR SRFSNANMEN
     RAASPEVPKR SLQDIVSKIR TEKEANKNQL VQSALPPKQS RPIHASLNAF LNSDLAADQT
     NAGPTEGRSF FLPAFRHLPD WTSGALRFDA MKDGVPVFVK SGKNGVRLGQ SGDHESINAV
     GIPEEDEQIF VSMDKLQEEV RELHDHDAML QREAEKLQRE VNQLQSELKR YKTRRPSDSA
     IGSDSDGSFG RHAQANGYQL ETQIAQLQNR LDQASRQVGV QDIHSTALAA ERDEALHQAS
     LARERAKRLQ VELESTQKDL EFTLQYRKDK DALQNENITL RTTNEELKLK NEALSQANQE
     LSNKYDKLRR EHLSAQKDLA STQEELASLR KKYDAILEEK KLIAQDHASM ERNNESYFKE
     TKKLQAQIAA RDQHIADLKR GINTRDQMID NIGGLTTNTA VIELNAELEA EIERLKQKLQ
     NQATRTDDRD GSSSAKESRI RALKEQNLEL EYEKQKLLEE NQRLRAEYEE LKGQWIDDRH
     KVVRLNQLLT KNNTEFLKTM NDNTEDCVRL EEDFKNKEAS LRQKLERREA AIKKVKQLTA
     QINEISQREL LGKPTKVTRI IEPKNGTSTG YAANDLTGKS GTMNVDDDPT TELNLTQGTD
     FASVMDNEIA KLRQTYRDLE DQQRQIENDN TTQPSQTGDA VQSKNQPVGI LKKSSRFGFD
     EDTGRFSVAS HHSEDESVKT ATTSKSRRPS SMGVQGQETP RPASRVRRNS DNPTITTQTD
     KQSSLGHSIP ALSKEARRVL DQICNHKSDN CNVCVRIAAN GHHVSPSTKA PITVEDMRKG
     KKTVRVDRPV PVSDRAVKGH GNYEEEPTMR PAMAPGDALA VLIKEISDEI EHLQMELKHM
     NELYFSLDKS TGQRERRRIM GEIKKLQAEL ETKSGQLYKL HDVLEGQKNA GQLMDDSEID
     ITILSDLLRV NGATENREAS WNGFDE
//