ID G4U978_NEUT9 Unreviewed; 449 AA.
AC G4U978;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE SubName: Full=DUF605-domain-containing protein {ECO:0000313|EMBL:EGZ76851.1};
GN ORFNames=NEUTE2DRAFT_146556 {ECO:0000313|EMBL:EGZ76851.1};
OS Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ76851.1, ECO:0000313|Proteomes:UP000008513};
RN [1] {ECO:0000313|EMBL:EGZ76851.1, ECO:0000313|Proteomes:UP000008513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Genetics 189:55-69(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Endosome membrane {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the VTA1 family.
CC {ECO:0000256|ARBA:ARBA00007895}.
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DR EMBL; GL890999; EGZ76851.1; -; Genomic_DNA.
DR AlphaFoldDB; G4U978; -.
DR STRING; 510952.G4U978; -.
DR eggNOG; KOG0917; Eukaryota.
DR HOGENOM; CLU_030378_0_0_1; -.
DR Proteomes; UP000008513; Unassembled WGS sequence.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032511; P:late endosome to vacuole transport via multivesicular body sorting pathway; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.420; Immunoglobulin FC, subunit C; 1.
DR Gene3D; 1.25.40.270; Vacuolar protein sorting-associated protein vta1; 1.
DR InterPro; IPR044538; Vta1-like.
DR InterPro; IPR039431; Vta1/CALS_N.
DR InterPro; IPR023175; Vta1/CALS_N_sf.
DR InterPro; IPR041212; Vta1_C.
DR PANTHER; PTHR46009; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG; 1.
DR PANTHER; PTHR46009:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG; 1.
DR Pfam; PF04652; Vta1; 1.
DR Pfam; PF18097; Vta1_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 21..180
FT /note="Vta1/callose synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04652"
FT DOMAIN 412..447
FT /note="Vta1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18097"
FT REGION 178..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 205..219
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 331..345
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 349..370
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 47871 MW; A1A74B9F89E0E985 CRC64;
MTDNITIPAA VKAADINLWK CATKALQLQS VKPEIAYWCN YWVVNQILNR GLHKENDEMM
TYTMDLMGKL EQARFIPPPF TTSLADCCSL QAKAEHPNED AYTDDEVGQV VVDRFAQETL
DRAERVVKAN KVTQQTAMTF DAAATFFHLV NIWGPPDEET QQKIKYAKWN AARIAKAIKE
GRDPNESNPK REEPQLPALD PSDPEVQTLT GSVEKTSPPP LSVTVEEVPD RDLQRTDAAG
VSLPISPASA GPSPISEAEL KLPGVPSGLA EPAPSTVSLD LDTPVSAPTH NPVNYRPEPD
LPSAPSALSS YPDRDISMPD AGTAAWTPGA DRQPPAPPVV PPTFAPSAPS TAAVVSPPVN
QPTDFSFQNP APAAAQAPAV PSLQPVPTPL AVSAATYASS QVAGGFTTDE AAMASAQKHA
KWAISALNFE DVPTAVKELR KALEVLGAA
//
