ID G4UJZ7_NEUT9 Unreviewed; 543 AA.
AC G4UJZ7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein {ECO:0000259|Pfam:PF17851};
GN ORFNames=NEUTE2DRAFT_106443 {ECO:0000313|EMBL:EGZ72602.1};
OS Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ72602.1, ECO:0000313|Proteomes:UP000008513};
RN [1] {ECO:0000313|EMBL:EGZ72602.1, ECO:0000313|Proteomes:UP000008513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Genetics 189:55-69(2011).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
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DR EMBL; GL891217; EGZ72602.1; -; Genomic_DNA.
DR AlphaFoldDB; G4UJZ7; -.
DR STRING; 510952.G4UJZ7; -.
DR eggNOG; ENOG502SM8A; Eukaryota.
DR HOGENOM; CLU_016508_2_1_1; -.
DR OMA; KLTEAPH; -.
DR Proteomes; UP000008513; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd09000; GH43_SXA-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Reference proteome {ECO:0000313|Proteomes:UP000008513}.
FT DOMAIN 328..529
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 15
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 188
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 128
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 543 AA; 62164 MW; 5DA5A5F4323A4AEC CRC64;
MPLVKNPILP GFNPDPSVLR VGQDYYIATS TFEWYPGVQI HHSTDLANWT LLTRPLNRKS
QLDMRGDPDS CGVWAPCLSH DGDKFWLVYT DVKRKDGSFK DAHNYIVWAD KIDGEWSDPV
YVNSSGFDPS LFHDPDSGKK YFVNMLWDHR RRPLLFAGIA VQEWDAKTKK LVGERKNVYQ
GTELALAEAP HVYKRNGWYY LLIAEGGTGY EHACTLARSK NIWGPYETHP EKHVLTSKDH
PRAVLQRAGH GDIVETEDGR TYLVHLTGRP TTQLRRCVLG RETAIQECYW KDDWLYVKNG
PVPSLWVDLL GERDESKYWE EKRYTFKDGL HKDFQWLRTP ETERIFNVKD DKLTVIGREA
IGSWFEQALV ARRQEHFSYD AETVIDFSPT DERQFAGLTA YYCRYNFFYL TVTAHSDGQR
ELLIMSSEAS WPIGNLNTPY VPYVQIPNEG KVKLALTIRG NQLQFYYAVL GSGDEEPKKI
GPVFDASIVS DECGGHQQHG SFTGAFVGVA ASDLNGLAAE AKFDYLLYKP VKNQQDAYVR
DNE
//
