ID G4V9U7_SCHMA Unreviewed; 206 AA.
AC G4V9U7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=Synaptosomal-associated protein {ECO:0000256|RuleBase:RU003496};
OS Schistosoma mansoni (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_034120.1};
RN [1] {ECO:0000313|Proteomes:UP000008854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA Zerlotini A., Dunne D.W., Berriman M.;
RT "A systematically improved high quality genome and transcriptome of the
RT human blood fluke Schistosoma mansoni.";
RL PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN [2] {ECO:0000313|WBParaSite:Smp_034120.1}
RP IDENTIFICATION.
RC STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_034120.1};
RG WormBaseParasite;
RL Submitted (DEC-2018) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Synapse, synaptosome
CC {ECO:0000256|ARBA:ARBA00034102}.
CC -!- SIMILARITY: Belongs to the SNAP-25 family.
CC {ECO:0000256|ARBA:ARBA00009480, ECO:0000256|RuleBase:RU003496}.
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DR RefSeq; XP_018648226.1; XM_018793745.1.
DR AlphaFoldDB; G4V9U7; -.
DR STRING; 6183.G4V9U7; -.
DR EnsemblMetazoa; Smp_034120.1; Smp_034120.1; Smp_034120.
DR GeneID; 8343268; -.
DR KEGG; smm:Smp_034120; -.
DR WBParaSite; Smp_034120.1; Smp_034120.1; Smp_034120.
DR CTD; 8343268; -.
DR eggNOG; KOG3065; Eukaryota.
DR HOGENOM; CLU_096939_0_0_1; -.
DR InParanoid; G4V9U7; -.
DR OMA; GMIQINE; -.
DR OrthoDB; 388796at2759; -.
DR PhylomeDB; G4V9U7; -.
DR Proteomes; UP000008854; Unassembled WGS sequence.
DR ExpressionAtlas; G4V9U7; differential.
DR GO; GO:0043005; C:neuron projection; IEA:UniProtKB-KW.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
DR CDD; cd15885; SNARE_SNAP25C; 1.
DR CDD; cd15889; SNARE_SNAP25N_23N; 1.
DR Gene3D; 1.20.5.110; -; 2.
DR InterPro; IPR000928; SNAP-25_dom.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR19305; SYNAPTOSOMAL ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR19305:SF14; SYNAPTOSOMAL-ASSOCIATED PROTEIN-RELATED; 1.
DR Pfam; PF00835; SNAP-25; 1.
DR SMART; SM00397; t_SNARE; 2.
DR SUPFAM; SSF58038; SNARE fusion complex; 2.
DR PROSITE; PS50192; T_SNARE; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008854};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Synaptosome {ECO:0000256|ARBA:ARBA00022599}.
FT DOMAIN 23..85
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT DOMAIN 142..204
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT COILED 61..88
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 206 AA; 23348 MW; 237D4933A2D3BD99 CRC64;
MSSMMDESQV PMTEYEQIKF KMNQTTDESL EASRRMMALC EEAKEAGIST LVMLDDQGEQ
LDRINEGMDQ INQDMKDAEK NLDDLNKCCG LCVLPWNKVK KKDDYTKQLK DEDMRGGDGP
RIIVDQNGMG PTGGYITRIT NDAREDEMDQ NLQEVSGMIG NLRNMAIDMG SEINQQNVQV
ERIQIKAKSN AERIKKANEQ ASKLLK
//
