ID G4VKM6_SCHMA Unreviewed; 730 AA.
AC G4VKM6;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE SubName: Full=Putative gtp binding protein {ECO:0000313|WBParaSite:Smp_169280.1};
OS Schistosoma mansoni (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_169280.1};
RN [1] {ECO:0000313|Proteomes:UP000008854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA Zerlotini A., Dunne D.W., Berriman M.;
RT "A systematically improved high quality genome and transcriptome of the
RT human blood fluke Schistosoma mansoni.";
RL PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN [2] {ECO:0000313|WBParaSite:Smp_169280.1}
RP IDENTIFICATION.
RC STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_169280.1};
RG WormBaseParasite;
RL Submitted (DEC-2018) to UniProtKB.
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DR RefSeq; XP_018652835.1; XM_018797833.1.
DR AlphaFoldDB; G4VKM6; -.
DR STRING; 6183.G4VKM6; -.
DR EnsemblMetazoa; Smp_169280.1; Smp_169280.1; Smp_169280.
DR GeneID; 8347719; -.
DR KEGG; smm:Smp_169280; -.
DR WBParaSite; Smp_169280.1; Smp_169280.1; Smp_169280.
DR CTD; 8347719; -.
DR eggNOG; KOG0463; Eukaryota.
DR HOGENOM; CLU_012821_2_0_1; -.
DR InParanoid; G4VKM6; -.
DR OrthoDB; 129286at2759; -.
DR PhylomeDB; G4VKM6; -.
DR Proteomes; UP000008854; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd04165; GTPBP1_like; 1.
DR CDD; cd03694; GTPBP_II; 1.
DR CDD; cd03708; GTPBP_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR035531; GTPBP1-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF9; GTP-BINDING PROTEIN 1; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008854}.
FT DOMAIN 209..439
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 92..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 704..730
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 730 AA; 79848 MW; 009A6BAEABE68943 CRC64;
MDGNPSTLSI LSDKYVFLNP NEDQFVRIKN YLDIELDNGQ GECFLELGIG DGQCPGLTPQ
EMNQSVCTAE RLADSLSSHL IYLRDRWITA GSQSSATTTT QSGSGVDTLT RPSSVDNGHS
SPHRHTLTSS SGESKTKGNS VNIDDGIKSK QNSISTDNNK ELSSQDKSET NITDTTSTIS
SSSSNSSSAT TGCLVKEYLL RRKTASDDFV DVRVAVVGNV DAGKSTLLGV LTHGELDNGR
GLARLRLLRH KHEAESGRTS SVAHDILGFN SIGQVVNKPI HGHLNWSEIC EASAKVITFI
DLAGHERYLK TTIFGMTGHA PDYVMFMVGA NAGVIGMAKE HLGLALALCV PVFVVVTKID
MCPPNVLHET MNLLFRILKS PGCRKIPALI SSTDDVICCA TNFTSERMCP IFSVSNVNGT
NLDLLKLFLN LLPSRSEPRL NELAHFQIDE IFSVQGVGTV ISGTCLSGII KLNDILLLGP
DLSGQFNPIS IKSIQRKRLS VNYVRGGQTA SFALKKLRRN QVRKGMVLLA PESKPKACIE
FIAEVLILHH PTTISVGYQA MVHAGPVRQT ATILKLNSHE RLRTGDKDMV VFRFIKSPEY
LYTGLRLIFR EGKTKAVGTV KELVPYSASI QQNPRAKLYK RYATSKTNQP MNNTVTDEIK
TLNLSNTSSI PKSTEYISTT TTTNTTSQPD TTELSNIPVS DLLTSNNINA PANSRQRKHH
YHRTRKDITE
//
