ID   G4XIJ3_CRASO            Unreviewed;       238 AA.
AC   G4XIJ3;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   22-FEB-2023, entry version 31.
DE   SubName: Full=Sine oculis-like transcription factor Six1/2B {ECO:0000313|EMBL:AEP43998.1};
GN   Name=Six1/2B {ECO:0000313|EMBL:AEP43998.1};
OS   Craspedacusta sowerbii (Freshwater jellyfish).
OC   Eukaryota; Metazoa; Cnidaria; Hydrozoa; Trachylinae; Limnomedusae;
OC   Olindiidae; Craspedacusta.
OX   NCBI_TaxID=128124 {ECO:0000313|EMBL:AEP43998.1};
RN   [1] {ECO:0000313|EMBL:AEP43998.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Hroudova M., Vojta P., Strnad H., Krejcik Z., Ridl J., Paces J., Vlcek C.,
RA   Paces V.;
RT   "Regulatory role of Pou and Six homeodomain transcription factors in
RT   sensory and nerve functions in hydrozoan jellyfish Craspedacusta
RT   sowerbyi.";
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
CC       ECO:0000256|RuleBase:RU000682}.
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DR   EMBL; JF819720; AEP43998.1; -; mRNA.
DR   AlphaFoldDB; G4XIJ3; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR031701; SIX1_SD.
DR   PANTHER; PTHR10390; HOMEOBOX PROTEIN SIX; 1.
DR   PANTHER; PTHR10390:SF61; HOMEOBOX PROTEIN SIX2; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   Pfam; PF16878; SIX1_SD; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}.
FT   DOMAIN          172..232
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        174..233
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
SQ   SEQUENCE   238 AA;  27750 MW;  577FAD17FDD52EC2 CRC64;
     MHSGFSLNKN FSTNIYSLLS PQMQSAPIRL EATGETSIES GNKKSWACST HIDRQMPVFS
     EHHIELVSEC LISSGQPERL RRFLWAVSKD QPVGDSEAAL VARAYVYFWQ KDFDSLYRVL
     QMRNFSKKNH ERLQSLWRIA HYLEAEAQRG RPLGAVGKYR IRRKFPLPRT IWDGEQNSYC
     FREHARRALH EAYKKNPYPT AKEKANLAAE TSLSVTQVSN WFKNRRQRVR ASESRKSR
//